Download RGUHS (Rajiv Gandhi University of Health Sciences) M.Pharma 2016 November (Master of Pharmacy) 1st Year 9338 Biopharmaceutics And Pharmacokinetics Revised Scheme 4 Previous Question Paper

Rajiv Gandhi University of Health Sciences
First Year M. Pharm Degree Examination - NOV 2016
[Time: 3 Hours]
[Max. Marks: 100]
Biopharmaceutics and Pharmacokinetics
(Revised Scheme 4)
Q.P. CODE: 9338
Your answers should be specific to the questions asked.
Draw neat, labeled diagrams wherever necessary.
LONG ESSAY (Answer any TWO)
2 X 20 = 40 Marks
1.
Explain various methods to improve bioavailability of poorly water-soluble drugs.
2.
Explain in detail non-per oral routes drug absorption.
3.
What are the assumptions of two compartmental model? Explain two compartmental open
model with i.v bolus drug administration. Derive various pharmacokinetic parameters of the
same.
SHORT ESSAY (Answer any FIVE)
5 X 10 = 50 Marks
4.
Write about physiological Pharmacokinetic model. Comment on statistical moment theory.
5.
Explain one compartment open model with extravascular drug administration along with
various pharmacokinetic parameters.
6.
Explain in detail about bio equivalence study.
7.
Write a note on Phase II Biotransformation reactions.
8.
Describe Noyes-Whitney's equation. Comment on similarity and dissimilarity factors.
9.
Dose adjustment in renal and hepatic impairment
SHORT NOTES
2 X 5 = 10 Marks
10.
Kinetics of protein binding
11.
Non renal excretion of drugs
* * * * *

---

Document Outline

• ??
• ??
• ??
• ??

---