First Year M Pharm Degree Examination - October 2016
[Time: 3 Hours] [Max. Marks: 100]
Biopharmaceutics and Pharmacokinetics
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(Revised Scheme 4)
Q.P. CODE: 9338
Your answers should be specific to the questions asked.
Draw neat, labeled diagrams wherever necessary.
Rajiv Gandhi University of Health Sciences
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LONG ESSAY (Answer any TWO) 2 X 20 = 40 Marks
- Explain various methods to improve bioavailability of poorly water-soluble drugs.
- Explain in detail non-per oral routes drug absorption.
- What are the assumptions of two compartmental model? Explain two compartmental open model with i.v bolus drug administration. Derive various pharmacokinetic parameters of the same.
SHORT ESSAY (Answer any FIVE) 5 X 10 = 50 Marks
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- Write about physiological Pharmacokinetic model. Comment on statistical moment theory.
- Explain one compartment open model with extravascular drug administration along with various pharmacokinetic parameters.
- Explain in detail about bioequivalence study.
- Write a note on Phase II Biotransformation reactions.
- Describe Noyes-Whitney’s equation. Comment on similarity and dissimilarity factors.
- Dose adjustment in renal and hepatic impairment
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SHORT NOTES 2 X 5 = 10 Marks
- Kinetics of protein binding
- Non renal excretion of drugs
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This download link is referred from the post: RGUHS M.Pharm 1st Year Last 10 Years 2011-2021 Question Papers || Rajiv Gandhi University of Health Sciences
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