Download RGUHS (Rajiv Gandhi University of Health Sciences) M.Pharma 2015 November (Master of Pharmacy) 1st Year 9283 Biopharmaceutics And Pharmacokinetics Rs 2 And Rs 3 Previous Question Paper

Rajiv Gandhi University of Health Sciences
First Year M.Pharm Degree Examination - NOVEMBER 2015
[Time: 3 Hours]
[Max. Marks: 100]
BIOPHARMACEUTICS AND PHARMACOKINETICS
(RS 2 & RS 3)
Q.P. CODE : 9283
Your answers should be specific to the questions asked.
Draw neat labeled diagrams wherever necessary.
LONG ESSAY (Answer any TWO)
2 X 20 = 40 Marks
1.
Explain how bioavailability can be determined from oral administration of solid dosage forms.
2.
Discuss the application of pharmacokinetics in dosage form design.
3.
Discuss the various in-vitro dissolution testing methods used in pharmaceutical product
evaluation.
SHORT ESSAY (Answer any FIVE)
5 X 10 = 50 Marks
4.
Illustrate the procedure for adjusting the dosage regimen of patients with renal impairment.
5.
Give the schematic representations of various pharmacokinetic models.
6.
Explain Michaelis-Menten equation.
7.
Discuss the various drug excretion pathways.
8.
Explain the various factors that influence drug metabolism.
9.
Discuss the kinetics of drug-protein binding.
SHORT NOTES
2 X 5 = 10 Marks
10.
Mention the importance of bioequivalence studies.
11.
Mention the significance of drug protein binding in drug therapy.
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