Rajiv Gandhi University of Health Sciences
First Year M. Pharm Degree Examination - NOV/DEC 2015
[Time: 3 Hours] [Max. Marks: 100]
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Biopharmaceutics and Pharmacokinetics
(Revised Scheme 4)
Q.P. CODE: 9338
Your answers should be specific to the questions asked.
Draw neat, labeled diagrams wherever necessary.
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LONG ESSAY (Answer any TWO) 2 X 20 = 40 Marks
- Explain in detail about physicochemical properties of drug absorption.
- What is pharmacokinetic model? Explain one compartment open model in detail with i.v bolus drug administration. Derive various pharmacokinetic parameters of the same.
- Explain multiple dosing with respect to i.v and oral route in detail.
SHORT ESSAY (Answer any FIVE) 5 X 10 = 50 Marks
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- Determination of rate of absorption by Wagner-Nelson Method
- In vitro, in vivo correlation
- Explain various causes of non-linearity reaction. With the help of equation, estimate Km and Vmax using Michaelis Menten equation.
- What are the various factors affecting rate of distribution?
- Physiological pharmacokinetic model
- Phase I reactions
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SHORT NOTES 2 X 5 = 10 Marks
- MRT for various compartmental model
- Therapeutic drug monitoring
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This download link is referred from the post: RGUHS M.Pharm 1st Year Last 10 Years 2011-2021 Question Papers || Rajiv Gandhi University of Health Sciences
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