Download RGUHS M.Pharm 2015 Nov 1st Year 9349 Advanced Pharmacology And Toxicology Revised Scheme 4 Question Paper

Rajiv Gandhi University of Health Sciences

First Year M. Pharm Degree Examination - NOV/DEC 2015

[Time: 3 Hours] [Max. Marks: 100]

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Advanced Pharmacology and Toxicology

(Revised Scheme 4)

Q.P. CODE: 9349

Your answers should be specific to the questions asked.

Draw neat, labeled diagrams wherever necessary.

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LONG ESSAY (Answer any TWO) 2 X 20 = 40 Marks

1. Write the pathophysiology, pharmacotherapy and critical analysis of rational use of drugs in asthma.
2. Write the molecular mechanisms involved in cell regulation.
3. Write the pathophysiology, pharmacotherapy and critical analysis of rational use of drugs in CHF.

SHORT ESSAY (Answer any FIVE) 5 X 10 = 50 Marks

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1. Write the intracellular signal transduction through mitogen-activated protein kinase (MAPK) and cytokine-activated Janus kinase (JAK) / signal transducer and activator of transcription (STAT) pathway.
2. Write the pathophysiology and pharmacotherapy of diabetes mellitus.
3. Write a note on female reproductive toxicity.
4. Write a note on in vitro tests for gene mutations in bacteria.
5. Pathophysiology and pharmacotherapy of myasthenia gravis

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6. Pathophysiology and pharmacotherapy of peptic ulcer

SHORT NOTES 2 X 5 = 10 Marks

1. G-protein coupled receptors
2. Biosynthesis of eicosanoids

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