First Year M. Pharm Degree Examination - NOV/DEC 2015
[Time: 3 Hours] [Max. Marks: 100]
Pharmacological Screening Methods and Clinical Evaluation
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(Revised Scheme 4)
Q.P. CODE: 9350
Your answers should be specific to the questions asked.
Draw neat, labeled diagrams wherever necessary.
LONG ESSAY (Answer any TWO) 2 X 20 = 40 Marks
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- Explain various preclinical models employed in the screening of anti-inflammatory drugs.
- Explain the various screening models of anticancer drugs.
- Explain the study design, ethics in patient selection and preserving their rights during clinical research.
SHORT ESSAY (Answer any FIVE) 5 X 10 = 50 Marks
- ICH guidelines for efficacy testing of drugs
- What is informed consent? Write its importance.
- Write the applications of Biomarker analysis.
- Write the basic principles involved in cell based assays.
- Explain the absorption of drug.
- Explain the various screening models of antiepileptic drugs.
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SHORT NOTES 2 X5 = 10 Marks
- Equivalence design
- Missing data management
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