Download RGUHS (Rajiv Gandhi University of Health Sciences) M.Pharma 2015 November (Master of Pharmacy) 1st Year 9351 Molecular Biology Revised Scheme 4 Previous Question Paper

Rajiv Gandhi University of Health Sciences
First Year M. Pharm Degree Examination - NOVEMBER 2015
[Time: 3 Hours]
[Max. Marks: 100]
Molecular Biology
(Revised Scheme 4)
Q.P. CODE: 9351
Your answers should be specific to the questions asked.
Draw neat, labeled diagrams wherever necessary.
LONG ESSAY (Answer any TWO)
2 X 20 = 40 Marks
1.
Explain various phases of cell cycle with a diagrammatic representation. Enumerate the various
checkpoints in cell cycles. Add a note on regulators and modifiers of cell cycle.
(10+4+6)
2.
What is gene expression? Explain the process of gene expression in eukaryotic cell. Enumerate
the genetic elements that control the gene expression.
(2+12+6)
3.
List various cell signaling and communication pathways between cells. What are biosensors?
Explain the construction and applications of biosensors.
(4+2+8+6)
SHORT ESSAY (Answer any FIVE)
5 X 10 = 50 Marks
4.
a) Explain the applications of rDNA technology.
b) Write a note on plasma membrane transport proteins and their inhibitors.
(5+5)
5.
Explain the events of apoptosis. Add a note on regulators of apoptosis.
(6+4)
6.
What is gene mapping? Name and explain various methods of gene mapping.
(2+2+6)
7.
Write the principles and applications of radio-ligand binding assay.
(5+5)
8.
With a neat-labeled diagram, explain the structure and functions of cell membrane and
mitochondria.
(5+5)
9.
a) Explain salient feature of various vectors used in gene therapy.
b) Explain the principle of antisense technology.
(5+5)
SHORT NOTES
2 X 5 = 10 Marks
10.
Write a note on pharmacological applications of animal tissue culture.
11.
Explain in brief the concept of human genome project.
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