Download RGUHS (Rajiv Gandhi University of Health Sciences) M.Pharma 2015 November (Master of Pharmacy) 1st Year 9202 Advanced Organic Chemistry Rs 2 And Rs 3 Previous Question Paper

Rajiv Gandhi University of Health Sciences
First Year M.Pharm Degree Examination ? NOVEMBER 2015
[Time: 3 Hours]
[Max. Marks: 100]
ADVANCED ORGANIC CHEMISTRY
(RS 2 & RS 3)
Q.P. CODE: 9202
Your answers should be specific to the questions asked.
Draw neat labeled diagrams wherever necessary.
LONG ESSAY (Answer any TWO)
2 X 20 = 40 Marks
1.
What are carbocation? Classify with example write the reaction in which they generated.
Explain the stability of carbocation.
2.
Give one synthesis and an example of medicinal agent belonging to the following heterocyclic
ring system a) Thiazoles b) Isoxazoles c) Benzimidazole d) Purine.
3.
Discuss the nucelophilic aliphatic substitution reaction. Write SN1 and SN2 mechanism, kinetic
energy and stereochemistry.
SHORT ESSAY (Answer any FIVE)
5 X 10 = 50 Marks
4.
Write the methods of synthesis and applications of acetoacetate esters.
5.
What is Grignard reagent? Write the mechanism of reaction involving Grignard reagent and its
synthetic applications?
6.
Discuss the mechanism and synthetic applications of aldol condensation.
7.
Write the synthetic route for Quinoline and Quainazoline.
8.
Explain the stereochemistry of steroids.
9.
Explain the oxidation reduction reaction, regents used, mechanism and applications
SHORT NOTES
2 X 5 = 10 Marks
10.
Microwave irradiation techniques.
11.
Hyperconjucation.
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