First Year M. Pharm Degree Examination – NOVEMBER 2015
[Time: 3 Hours] [Max. Marks: 100]
Clinical Pharmacy Practice
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(Revised Scheme 4)
Q.P. CODE: 9395
Your answers should be specific to the questions asked.
Draw neat, labeled diagrams wherever necessary.
LONG ESSAY (Answer any TWO) 2 X 20 = 40 Marks
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- What are the roles and responsibilities of a clinical pharmacist on day to day basis in a tertiary care hospital? Discuss in detail the protocol and importance of Drug utilization review programme of a hospital.
- a) Explain. How would you assess acute myocardial infraction with the aid of laboratory investigations?
b) Define anemia. Discuss the laboratory assessment of Anemia. - Describe the applications of various clinical pharmacokinetic models. Add a note on physiological determinants of drug clearance and volumes of distribution.
SHORT ESSAY (Answer any FIVE) 5 X 10 = 50 Marks
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- Discuss various clinical laboratory tests used to evaluate disease states in liver dysfunction.
- Discuss briefly various guidelines for good clinical research practice and ethical requirements.
- Discuss various steps involved in systematic approach of answering a Drug Information Query.
- Write the importance of communication skills in clinical pharmacy practice.
- Discuss the role of clinical pharmacist in adverse drug reaction (ADR) management.
- Explain about Dose adjustment in hepatic failure and renal failure patients
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SHORT NOTES 2 X5 =10 Marks
- Calculation of loading and maintenance doses for narrow therapeutic index drugs
- Various estimation methods and determinants of bioavailability in clinical pharmacokinetics
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