First Year M. Pharm Degree Examination - Oct/Nov 2014
[Time: 3 Hours] [Max. Marks: 100]
MEDICINAL CHEMISTRY I (DRUG DESIGN)
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PAPER III
(RS 2 & RS 3)
Q.P. CODE: 9233
Your answers should be specific to the questions asked.
Draw neat labeled diagrams wherever necessary. Answer all questions
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LONG ESSAY (Answer any TWO) 2 X 20 = 40 Marks
- a) Explain about Drug receptor interactions in biological activity
b) Write various microbial conversions used in the preparation of drugs with examples. - Explain various aspects governing prodrug design.
- Write various applications of molecular & quantum mechanics in drug design.
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SHORT ESSAY (Answer any FIVE) 5 X 10 = 50 Marks
- Write about production of drugs from recombinant DNA technology.
- Explain the role of enzyme inhibitors in rational drug design give suitable examples
- Classify proton pump inhibitors and explain the mechanism of them in gastric acid secretion inhibition.
- Explain about Hansch and Free Wilson analysis.
- Write the therapeutic aspects of Epitope mapping.
- Write about any two mathematical methods for the analysis of QSAR.
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SHORT NOTES 2 X 5 = 10 Marks
- Add a note on Physical properties related to potency of drugs.
- Add a note on immunosuppressive agents.
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This download link is referred from the post: RGUHS M.Pharm 1st Year Last 10 Years 2011-2021 Question Papers || Rajiv Gandhi University of Health Sciences
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