E!E{laaj?a? Eignejmv Isity of Health Sciences
First Year M. Pharm Degree Examination - Nov 2
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[Time: 3 Hours] [Max. Marks: 100]
Molecular Biology
(Revised Scheme 4)
Q.P. CODE: 9351
Your answers should be specific to the questions asked.
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Draw neat, labeled diagrams wherever necessary.
LONG ESSAY (Answer any TWO) 2 X 20 = 40 Marks
- Explain the different phases of cell cycle and factors regulating progression of cells at checkpoints.
- a) Explain the extrinsic or death receptor pathway of apoptosis and factors simulating this pathway.
b) Explain the medical applications of adult stem cells and embryonic stem cells. - a) Explain the mechanism of drug transport across the plasma cell membrane.
b) Describe biosensors and their applications.
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SHORT ESSAY (Answer any FIVE) 5 X 10 = 50 Marks
- Explain the principles and applications of MTT assay.
- Explain gene therapy.
- Explain the applications of flow cytometer and western blot unit in molecular studies.
- Explain DNA based diagnosis of genetic diseases.
- Explain the formation and uses of restriction fragment length polymorphism.
- Explain applications of nucleic acid technologies and catalytic antibodies in molecular pharmacology.
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SHORT NOTES 2 X 5 = 10 Marks
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- Applications of microarray technology
- Enzymes used in molecular cloning
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