Download RGUHS (Rajiv Gandhi University of Health Sciences) M.Pharma 2014 November (Master of Pharmacy) 1st Year 9351 Molecular Biology Revised Scheme 4 Previous Question Paper

Rajiv Gandhi University of Health Sciences
First Year M. Pharm Degree Examination - Oct/Nov 2014
[Time: 3 Hours]
[Max. Marks: 100]
Molecular Biology
(Revised Scheme 4)
Q.P. CODE: 9351
Your answers should be specific to the questions asked.
Draw neat, labeled diagrams wherever necessary.
LONG ESSAY (Answer any TWO)
2 X 20 = 40 Marks
1.
Explain the different phases of cell cycle and factors regulating progression of cells at
checkpoints.
2.
a) Explain the extrinsic or death receptor pathway of apoptosis and factors simulating this
pathway.
b) Explain the medical applications of adult stem cells and embryonic stem cells.
3.
a) Explain the mechanism of drug transport across the plasma cell membrane.
b) Describe biosensors and their applications.
SHORT ESSAY (Answer any FIVE)
5 X 10 = 50 Marks
4.
Explain the principles and applications of MTT assay.
5.
Explain gene therapy.
6.
Explain the applications of flow cytometer and western blot unit in molecular studies.
7.
Explain DNA based diagnosis of genetic diseases.
8.
Explain the formation and uses of restriction fragment length polymorphism.
9.
Explain applications of nucleic acid technologies and catalytic antibodies in molecular
pharmacology.
SHORT NOTES
2 X 5 = 10 Marks
10.
Applications of microarray technology
11.
Enzymes used in molecular cloning
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