Rajiv Gandhi University of Health Sciences
First Year M.Pharm Degree Examination — May 2013
--- Content provided by FirstRanker.com ---
[Time: 3 Hours] [Max. Marks: 100]
ADVANCED ORGANIC CHEMISTRY
(RS 2 & RS 3)
Q.P. CODE: 9202
Your answers should be specific to the questions asked.
--- Content provided by FirstRanker.com ---
Draw neat labeled diagrams wherever necessary. Answer all questions
LONG ESSAY (Answer any TWO) 2 X 20 = 40 Marks
- a) Discuss the stereochemistry of Steroids
b) Discuss the chemistry of tetrazole nucleus - a) Describe the method of preparation and synthetic application of aceto acetic ester
--- Content provided by FirstRanker.com ---
b) Explain the mechanism of elimination reaction with examples - Outline the scheme for the synthesis and chemical properties of some pharmaceutical applications of:
a) Pyrimidines b) Dibenzapines c) Isoxazole
SHORT ESSAY (Answer any FIVE) 5 X 10 = 50 Marks
- Describe the concepts of retrosynthesis with examples.
- Discuss the synthesis and chemistry of quinoline ring and give some drug molecules having that basic ring structure.
- Describe different types of chemical bonds and their properties
- Outline the mechanism of Friedel-Crafts acylation and alkylation with examples.
- Discuss the chemical nature of free radicals and carbenes
- Describe the reaction mechanism and the reagents involved in oxidation and reduction reactions
--- Content provided by FirstRanker.com ---
--- Content provided by FirstRanker.com ---
SHORT NOTES 2 X 5 = 10 Marks
- Microwave irradiation techniques in the synthesis of drugs with examples.
- Hydrogenation reactions with heterogeneous catalysts
--- Content provided by FirstRanker.com ---
This download link is referred from the post: RGUHS M.Pharm 1st Year Last 10 Years 2011-2021 Question Papers || Rajiv Gandhi University of Health Sciences