RGUHS M.Pharm 1st Year Last 10 Years 2011-2021 Question Papers || Rajiv Gandhi University of Health Sciences
FAFER 111
A Revised Scheme 2)
Q.P. CODE : 9233
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Your answers should be specific to the questions asked.
Draw neat labeled diagrams wherever necessary. Answer all questions
LONG ESSAY (Answer any TWO) 2 X 20 = 40 Marks
- a) Explain the development of t-PA as therapeutic agent.
b) Write about microbial transformation. - Explain various mathematical methods for the analysis of QSAR.
- a) Give the chemistry and uses of irreversible gastric proton pump inhibitors.
b) Explain the role of quantum mechanics in drug design
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SHORT ESSAY (Answer any FIVE) 5 X 10 = 50 Marks
- Write various approaches of enzyme inhibitors in rational drug design.
- How microbial conversions are useful as tools in the preparation of drugs.
- Enumerate the different methods in the calculation of partition co-efficients.
- Explain about Epitope mapping and human growth hormone in Recombinan-DNA technology.
- Write various drug receptor interactions in quantitative analysis of SAR.
- Classify immune response agents with examples and write their SAR.
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SHORT NOTES 2 X5 = 10 Marks
- Add a note on Hansch analysis.
- Hydrogen bonding with respect to biological activity
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