Download RGUHS M.Pharm 2010 Oct 2010 Oct 7924 Advanced Pharmaceutical Chemistry Revised Scheme Question Paper

Download RGUHS (Rajiv Gandhi University of Health Sciences) M.Pharma 2010 October (Master of Pharmacy) 2010 Oct 7924 Advanced Pharmaceutical Chemistry Revised Scheme Previous Question Paper

7924_2010_1_S203
Rajiv Gandhi University of Health Sciences
First Year M. Pharm Degree Examination ? October - 2010

[Time: 3 Hours]
[Max. Marks: 100]
ADVANCED PHARMACEUTICAL CHEMISTRY

(Revised Scheme)
Q.P. CODE : 7924
Your answers should be specific to the questions asked.
Draw neat labeled diagrams wherever necessary. Answer FOUR questions
ANSWER ANY FOUR
4 X 25 = 100 Marks
1.
a) Discuss with examples, the formation and stabilites of carbocations and write the influence
of substituents on their stabilities
b) How do you say that carboxylic acids are more acidic than phenols based on resonance
2.
a) Give an account of the methods of determination of reaction mechanisms
b) Discuss the mechanism and applications pf pinacol pinacolone rearrangement
3.
Write short notes on:
a) Beckmann rearrangement b) Benzilic acid rearrangement
c) Schmidt reaction d) Benzoin condensation
4.
a) Explain with a suitable example the salient features of a substitution
b) Discuss the steriochemical evidence in favour of this reaction
c) How can you say that SN 1 reactions proceeds with inversion and recemization in which
inversion exceeds
5.
Give an account of
a) Aromatic nucelophilic substituation b) Friedel ? Crafts alkylation and acylation
c) Cannizaro reaction d) Favorski rearrangement
6.
Write briefly on:
a) R and S configuration b) Heterogenous catalysis
c) Diels ? Alder reaction d) SIgmatropic rearrangement
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