Download RGUHS M.Pharm 2010 May 1st Year 9234 Medicinal Chemistry II Natural Products Paper Iv Revised Scheme 2 Question Paper

Download RGUHS (Rajiv Gandhi University of Health Sciences) M.Pharma 2010 May (Master of Pharmacy) 1st Year 9234 Medicinal Chemistry II Natural Products Paper Iv Revised Scheme 2 Previous Question Paper

9234_2009_1_S44.doc
Rajiv Gandhi University of Health Sciences
First Year M.Pharm Degree Examination ? May 2010

[Time: 3 Hours]
[Max. Marks: 100]
MEDICINAL CHEMISTRY - II (NATURAL PRODUCTS)


PAPER IV

(Revised Scheme 2)

Q.P. CODE : 9234
Your answers should be specific to the questions asked.
Draw neat labeled diagrams wherever necessary. Answer all questions

LONG ESSAY (Answer any TWO)
2 X 20 = 40 Marks
1.
Explain the structural elucidation of emetine
2.
What are penicillins? Explain the chemistry, stability and biological significance of various
penicillins
3.
a) Explain the metabolism of purines
b) Explain the SAR of adrenal cortex hormones
SHORT ESSAY (Answer any FIVE)
5 X 10 = 50 Marks
4.
Explain the chemistry and biological importance of pyrimidine related antineoplastic agents
5.
Write the synthesis of
a) a -lactamase resistant cephalosporin
b) an antipseudomonal cephalosporin
6.
Explain the chemistry and SAR of other fused Betalactam systems
7.
Explain the chemistry and importance of any two antidiabetic crude drugs
8.
What are cardiac glycosides? Explain their chemistry and SAR
9.
List out the various preparations of insulin. Write about storage and release of insulin
SHORT NOTES
2 X 5 = 10 Marks
10. Morphine
derivatives
11. Antiparasitic agents
* * * * *

---