Download RGUHS (Rajiv Gandhi University of Health Sciences) M.Pharma 2010 May (Master of Pharmacy) 1st Year 9243 Pharmacological Screening Methods And Clinical Evaluation Paper III RS 2 Previous Question Paper
Rajiv Gandhi University of Health Sciences
First Year M.Pharm Degree Examination ? May 2010
[Time: 3 Hours]
[Max. Marks: 100]
PHARMACOLOGICAL SCREENING METHODS
AND CLINICAL EVALUATION
PAPER III
(Revised Scheme 2)
Q.P. CODE : 9243
Your answers should be specific to the questions asked.
Draw neat labeled diagrams wherever necessary. Answer all questions
LONG ESSAY (Answer any TWO)
2 X 20 = 40 Marks
1.
Discuss various phases of clinical trials. Explain the informed concent form
2.
Describe the various methods used to screen antidepressants drug. Discuss the methods by
which an anti anxiety drug can be differentiated from an antidepressants
3.
Are days for bioassays is going to be over. Explain principles, experimental models and
statistical design in a bioassays. Discuss the bio assay of insulin
SHORT ESSAY (Answer any FIVE)
5 X 10 = 50 Marks
4.
Preparation of investigational new drug / new drug application
5.
Screening of antiarrythmic drugs
6.
Physiological models in drug development
7.
Preclinical models for antiparkinsonism drug
8.
Movement of the drug through membrane
9.
Patch clamp technique
SHORT NOTES
2 X 5 = 10 Marks
10. Variability in drug action due to age, sex and weight
11. Volume of distribution
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This post was last modified on 11 June 2021