Q.P. CODE : 9243
Your answers should be specific to the questions asked.
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Draw neat labeled diagrams wherever necessary. Answer all questions
LONG ESSAY (Answer any TWO) 2 X 20 = 40 Marks
- Discuss various phases of clinical trials. Explain the informed consent form
- Describe the various methods used to screen antidepressant drugs. Discuss the methods by which an anti-anxiety drug can be differentiated from an antidepressant.
- Are days for bioassays going to be over? Explain principles, experimental models and statistical design in bioassays. Discuss the bio assay of insulin.
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SHORT ESSAY (Answer any FIVE) 5 X 10 = 50 Marks
- Preparation of investigational new drug / new drug application
- Screening of antiarrhythmic drugs
- Physiological models in drug development
- Preclinical models for antiparkinsonism drug
- Movement of the drug through membrane
- Patch clamp technique
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SHORT NOTES 2 X5 = 10 Marks
- Variability in drug action due to age, sex and weight
- Volume of distribution
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