Download RGUHS (Rajiv Gandhi University of Health Sciences) M.Pharma 2010 May (Master of Pharmacy) 1st Year 9283 Biopharmaceutics And Pharmacokinetics Revised Scheme 2 Previous Question Paper
Rajiv Gandhi University of Health Sciences
First Year M.Pharm Degree Examination ? May 2010
[Time: 3 Hours]
[Max. Marks: 100]
BIOPHARMACEUTICS AND PHARMACOKINETICS
(Revised Scheme 2)
Q.P. CODE : 9283
Your answers should be specific to the questions asked.
Draw neat labeled diagrams wherever necessary. Answer all questions
LONG ESSAY (Answer any TWO)
2 X 20 = 40 Marks
1.
Deduce equations to obtain pharmacokinetic parameters of a drug administered by oral route,
the drug undergoing absorption by first order kinetics and body acting as a single compartment
2.
Explain Michaelis-Menten equation and estimation of Km and Vmax
3.
Explain in detail the application of pharmacokinetics in new drug development and designing of
dosage forms
SHORT ESSAY (Answer any FIVE)
5 X 10 = 50 Marks
4.
Biological factors affecting absorption of drugs
5.
Write a note on therapeutic drug monitoring
6.
Explain with examples conjugation reactions for elimination of drugs
7.
Write on adjustment of dosage in renal and hepatic impairment
8.
Write on objectives and considerations in bioavailability study
9.
Explain significance and kinetics of protein binding
SHORT NOTES
2 X 5 = 10 Marks
10. Concept of loading and maintenance dose
11. Volume of distribution
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This post was last modified on 11 June 2021