Download RGUHS M.Pharm 2010 May 1st Year 9294 Advanced Pharmaceutical Analysis Paper Iv Revised Scheme 2 Question Paper

Download RGUHS (Rajiv Gandhi University of Health Sciences) M.Pharma 2010 May (Master of Pharmacy) 1st Year 9294 Advanced Pharmaceutical Analysis Paper Iv Revised Scheme 2 Previous Question Paper

9294_2008_1_S153
Rajiv Gandhi University of Health Sciences
First Year M.Pharm Degree Examination ? May - 2010

[Time: 3 Hours]
[Max. Marks: 100]
ADVANCED PHARMACEUTICAL ANALYSIS
PAPER IV








(Revised Scheme 2)

Q.P. CODE : 9294
Your answers should be specific to the questions asked.
Draw neat labeled diagrams wherever necessary. Answer all questions

LONG ESSAY (Answer any TWO)
2 X 20 = 40 Marks

1. Explain
the
bioassay of the following:
(a) Chorionic gonadotropin.
(b) Vasopressor activity.
(c) Urokinase.
2.
Explain the various techniques of microbiological assay of antibiotics with any one suitable
example.
3.
Give an account on the validation of HPLC analytical method as per ICH guidelines.
SHORT ESSAY (Answer any FIVE)
5 X 10 = 50 Marks

4.
Write methodology of sterility testing.
5.
Write the quality control tests for any two radiopharmaceuticals.
6.
What is the principle of Differential Thermal analysis? How does it differ from Differential
Scanning Calorimetry? Explain Differential Thermogram and application of Differential Thermal
analysis specifically to formulation development.
7.
Write the principle and the technique of microbiological assay of vitamins by turbidimetry by
taking any one vitamin as example.
8.
Explain the production and chemical nature of pyrogen and LAL test.
9.
Explain the applications of mass spectrometry to the quantitative analysis.
SHORT NOTES
2 X 5 = 10 Marks
10. Endotoxin and exotoxin.
11. Refractive
index.
* * * * *

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