CODE : 9203
Your answers should be specific to the questions asked.
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Draw neat labeled diagrams wherever necessary. Answer all questions
LONG ESSAY (Answer any TWO) 2 X 20 = 40 Marks
- Design the commercial production of Phenobarbitone with respect to
- reaction sequences and flow diagram
- material of construction of equipments
- purification procedure
- probable effluents and its management
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- What are possible industrial hazards? How can they controlled?
- Write a note on plant location
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- Explain merits and demerits of multipurpose plant vs dedicated plant for bulk drugs with specific examples
- What are various parameters considered for estimation of growth forecast of bulk drug?. Illustrate your answer with examples
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SHORT ESSAY (Answer any FIVE) 5 X 10 = 50 Marks
- Explain the Govt policies and regulatory authorities involved in controlling bulk drug production
- Discuss layout and construction commercial aspects of bulk drug production
- Write the concept methodology, applications and limitation of combinatorial synthesis of drug production
- Write the flow diagram and reaction sequence for industrial production of clotrimazole
- Explain commercial production and flow diagram of mebendazole
- Enumerate historical development of bulk drug industry in India
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SHORT NOTES 2 X5 = 10 Marks
- Enumerate effects of multinational companies on bulk drug production of India
- Write notes on a) Private enterprises b) foreign collaboration
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