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Download PGI PG 2020 May Physio Solved Question Paper

Download PGIMER (Post Graduate Institute of Medical Education & Research, Chandigarh) 2020 May Physio Solved Question Paper

This post was last modified on 11 August 2021

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PGI Chandigarh Last 10 Years 2011-2021 Solved Question Papers (PGIMER Previous Papers)

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All of these are correct of renal physiology except:
1. Sodium absorption occurs in DCT
2. Potassium is both secreted and absorbed in tubules
3. Glucose is reabsorbed in DCT
4. All
5. None
Blood brain barrier is absent in ?
1. Adenohypophysis
2. Neurohypophysis
3. Hypothalamus
4. Thalamus
5. None

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True regarding HbA2 is/are?
1. It has more capacity to carry oxygen
2. Concentration is more than HbA
3. Level is increased in Thalasemia
4. Consists of 2 alpha and 2 beta chains
5. None of the above
TRUE statement(s) regarding "loop of Henley" in kidney is/are?
1. Ascending limb actively absorbs Na
2. Ascending limb actively absorbs Cl
3. Ascending limb secretes water in lumen
4. Descending limb secretes water
5. Descending limb receives hyperosmolar fluid from PCT
Iodine is transported to the thyroid gland by ?
1. Active transport
2. Diffusion
3. Passive transport
4. Pinocytosis
5. None
Antioxidant effects are shown by?
1. Vitamin C
2. Vitamin E
3. Selenium
4. Zinc
5. Vitamin B
Right combination of sensory receptor and sensation carried by them includes?
1. Krouse's bulb - pressure
2. Pacinian corpuscels - vibration
3. Meissner's corpuscles - pressure
4. Ruffini's end organs - pressure
5. Merkel's disc - cold temperature

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TRUE regarding hypoxemia is/are?
1. Decrease in ventilation
2. Decrease in delivery of oxygen to tissues
3. Inadequate utilization of oxygen by tissues despite normal delivery of oxygen
4. Decreased oxygen pressure in blood
5. All of the above
According to WHO, normal semen findings are?
1. Volume - 1.5 ml
2. Concentration - 15 million/ml
3. Progressive motility - > 40%
4. Normal morphology - > 10%
5. Ph - < 6.3
Normal value of hydrogen ions in human fluids is?
1. 35 meq/L
2. 40 meq/L
3. 45 meq/L
4. 50 meq/L
5. None of the above
Which of the following play most important role in memory:
1. Synaptic network
2. Electric conduction network
3. Conductivity circuit
4. Conductivity network
5. None
Cyanide poisoning block K influx & Na efflux. But ATP reverse this effect. So true statement(s) related to mechanism of action of cyanide is/are:
1. K influx & Na efflux is regulated by Na-K ATPase enzyme
2. K influx & Na efflux is regulated by Na-K pump
3. ATP provide energy for this channel
4. Na-K ATPase channel is ATP independent
5. None

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True about Carbon monoxide poisoning:
1. CO has 100 times more affinity than 02 for Hb
2. Cause right side shifting of 02 dissociation curve
3. Oxygen-haemoglobin saturation curve becomes hyperbolic shape
4. Pulse oximetry can accurately detect level of CO
5. 10-15% level of CO normally may occur in healthy nonsmoker
Dead space is increased in:
1. Positive pressure ventilation
2. Extension of neck
3. Anticholinergic drug
4. Endotracheal tube intubation
5. Emphysema
Which of the following is true about cardiac innervation:
1. T1 -T5 is sympathetic supply
2. Inferior & superior cervical ganglia not involve in innervation
3. Parasympathetic supply is from vagus nerve
4. Great cardiac nerve arise from superior cervical ganglia
5. Inferior cervical ganglia gives off Inferior cardiac nerve
True about cortisol level in blood plasma:
1. Morning concentration is 17-18nmol/d1
2. Morning concentration is 5-23 microg/dL
3. Evening concentration is almost half of morning concentration
4. Evening concentration is 5-23 i.ig/dL
5. None
Saccadicc eye movement is controlled by:
1. Parietal lobe
2. Prefrontal lobe
3. Temporal lobe
4. Frontal cortex
5. Occipital lobe

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True about normal ECG:
1. Normal PR interval is 0.12-0.20 s
2. PR internal correspondence initiation of P wave to initiation of R wave
3. QT internal correspondence initiation of Q wave to initiation of T wave
4. Normal QRS interval < 0.12 s
5. Normal QTc interval
Which of the following is/are true about SIADH:
1. Desmopressin is used for treatment
2. Vasopressin level is inappropriately high
3. Plasma osmolality is higher than urine osmolality
4. Ted Osmolality of urine
5. Ted Osmolality of plasma
Which of the following feature(s) is/are suggestive of nehogrnic DI in comparison to central DI :
1. Desmopressin nasal spray restore urine output to normal level
2. Basal vasopressin level > 1 pg/ml
3. Normal posterior pituitary bright spot is not visible on MRI scan
4. Change in water loss during fluid deprivation test
5. None
True stateinent (s) about Olfactory system :
1. Olfactory mucosa cover upper 1/3 of nasal cavity
2. Olfactory pathway passes via thalamus to orbitofrontal cortex
3. Adaptation to odour develop only after 1-2 minutes
4. Olfactory receptors act via cAMP
5. Rate of olfactory nerve impulses change approximately in proportion to the logarithm of stimulus strength
Vomiting centre (s) involved in post - operative vomiting
1. Area postrema
2. Chemoreceptor trigger zone (CTZ)
3. Reticular formation located in medulla
4. Nucleus tractus solitarius
5. Basal ganglia

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True about special anatomy and Physiology of lung:
1. Surfactant prevent collapse of small alveoli into larger one
2. Larger alveoli has more tendency to collapse than smaller alveoli in absence of surfactant
3. Surfactant decrease chance of collapse
4. Surfactant increases surface tension
5. With surfactant, large alveoli tend to become smaller and smaller ones tend to become larger
All are true about acromegaly except :
1. Increased IGF-1 levels
2. Excessive growth occurs before fusion of the epiphyses of the long bones
3. Somatostatin analogues can be used
4. Growth hormone levels increased
5. Transsphenoidal surgical resection is the preferred primary treatment for pituitary adenoma
True statement (S) is/are:
1. Vasopressin increase only water reabsorption, not solute reabsorption
2. Aldosterone increase Na+ reabsorption from tubules
3. Glomerular filtrate of PCT has similar osmolarity as of plasma
4. Urine is hyperosmolar in early DCT
5. Generally urine osmolarity equals to plasma osmolarity
Rapidly adapting receptor(s) is/are:
1. Pain receptor
2. Pacinian corpuscles
3. Muscle spindle
4. Golgi tendon organs
5. Meissner corpuscles
Which of the following is/are true about normal level:
1. Total Calcium: 8.5-10.5 mg/dL
2. Sodium:135-145 mmol/L
3. Potassium: 3.5-5.1 mmol/L
4. Creatinine: 0.6-2.6 mg/dL
5. TSH level: 0.1-3.1 mIU/L

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True about Action Potential in skeletal muscle fibers and nerve fibres:
1. Skeletal muscle fibres conduction velocity is 1/4 of thick myelinated nerve fiber
2. Action potential of both qualitatively similar
3. Resting membrane potential almost same
4. Duration of action potential same in both
5. Action potential of both quantitively similar
Comprehension preserved in which of the follwing aphasia
1. Broca's aphasia
2. Conduction aphasia
3. Wernicke's aphasia
4. Gobal aphasia
5. Anomic aphasia
Tissue elevation of which of the following cause vasoconstriction :
1. Na+
2. K+
3. Mg
4. Ca2+
5. H+
Which of the following statement (s)is/are true changes at time of ovulation:
1. GnRH level decreases
2. Gonadotropin hormone surge
3. hCG surge
4. 1' Prostaglandins
5. Activation of proteolytic enzymes
Which of the following statements are true regarding diffusion of gas in lung -
1. Diffusion of gas is perfusion limited
2. CO, diffuses 20 times faster than 02
3. PO2 gradient is low between alveoli & blood vessel in case of restrictive lung disease
4. Diffusion of gas is decreased in emphysema
5. Diffusion capacity of 0, is 25

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Which of the following about renin angiotensin system are true -
1. Renin is produced by modified smooth muscles of glomerular capillary
2. Macula densa cells are part of this pathway
3. Angiotensinogen is converted to angiotensin by this pathway
4. Angiotensin converting enzyme is present in lung capillary endothelial cell
5. Angiotensin -II is decapeptide
True about renal tubular system are ?
1. Ascending loop of Henle actively pumps Chloride out of tubule
2. Ascending loop of Henle actively pumps Carbonate out of tubule
3. Descending loop of Henle is permeable to water
4. Ascending loop of Henle is impermeable to water
5. Descending loop of Henle receives hypotonic solution
True statement about nerve muscle physiology is ?
1. Action potential traverses along T tubules
2. Contraction is mainly because of extracellular calcium
3. Rynadine receptors sense the action potiential
4. actin pulls the myosin
5. ATP binds to myosin
True about copper metabolism is are ?
1. Intestinal absorption occurs in duodenum
2. 95% bond to albumin in the serum
3. Ceruloplosmin contains 6 atoms of copper
4. Failure to Synthesize ceruloplasmin causes wilson's disease
5. Copper excretion mainly occurs in urine
True about gas equation -
1. Gas constant is 0-9
2. PV = constant
3. PV = nRT
4. Diffusion is directly related to molecular weight of gas
5. Oxygen has more diffusion coefficient

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True about Prostaglandins -
1. Derived from lipooxygenase pathway
2. First product is PG G2
3. PG E2 causes vasoconstriction
4. PG F2a causes bronchoconstriction
5. PG 12 causes fall in BP
Which is/are feature(s) of prostaglandins -
1. 20 carbon atom compound
2. 10 carbon atom compound
3. Cyclopentane ring
4. -OH group at 15º position
5. Trans double bond at 10th position
Which of the following is/are effect of increased 2,3-DPG on oxygen-hemoglobin dissociation curve?
1. ? ed affinity of heamoglobin to oxygen
2. ? ed affinity of haemoglobin to oxygen
3. Left shift of oxygen-hemoglobin dissociation curve
4. Right shift of oxygen-hemoglobin dissociation curve
5. No change in oxygen-hemoglobin dissociation curve
Oxygen consumption by the heart is determined by ?
1. Intramyocardial tension
2. Contractile state of the myocardium
3. Initial length of the myocardial muscle fiber
4. Heart rate
5. Basal oxygen consumption of myocardium
Insulin causes intracellular shift of which of the following ion?
1. Na+
2. K+
3. Chloride
4. Calcium
5. Bicarbonate

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Hypothalmk pituitary axis (HPA) controls all except -
1. Thyroid
2. Parathyroid
3. Pancreas
4. Testis
5. Adrenals
True statement about male reproductive physiology -
1. Sertoli cells secrete Miillerian inhibiting substance (MIS)
2. Inhibin is released by sertoli cell
3. Primary spermatocyte is diploid
4. LH and FSH are steroidal in nature
5. Inhibin stimulates follicle-stimulating hormone (FSH)
Erythropoietin is/are produced by -
1. Juxtaglomerular cells
2. Interstitial cells of the peritubular capillary bed of the kidneys
3. Pars recta of PCT
4. Macula densa
5. Mesangial cell
True about carotid sinus -
1. Chemoreceptor
2. Present in early part of internal carotid artery
3. Has glomus cells
4. Baroreceptor
5. Supplied by glossopharyngeal nerve
Stress hyperglycemia occurs due to all except -
1. Increased level of ACTH
2. Increased level of cortisol
3. Decreased level of norepinephrine
4. Insulin resistance
5. Increased level of epinephrine

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Parasympathetic nerve stimulation results in:
1. Sphincter closure of gall bladder
2. Increased peristalsis
3. Decreased GIT motility
4. Detrusor muscle relaxation
5. Gall bladder musculature contraction
True about muscle spindle:
1. Group la fiber contain sensory afferent
2. Nuclear bag & nuclear chain fibers present in intrafusal muscle fiber
3. Motor supply by Aa fiber
4. Motor supply by y fiber
5. Secondary ending is stimulated by nuclear bag fiber
Hyperbaric oxygen therapy is/are used in:
1. Radiation induced proctitis
2. Tension pneumothorax
3. Bleomycin induced lung damage
4. Gasa angrene
5. Carbon mono-oxide poisoning
Peripheral cyanosis is/are associated with:
1. SLE
2. TAPVC
3. Atrial septal defect
4. Methemoglobinemia
5. Cardiogenic shock
Blood in foetus is/are formed by:
1. Liver
2. Lymph nodes
3. Spleen
4. Bone marrow
5. Yolk sac

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Important buffer system operating in blood:
1. Protein system buffer
2. Phosphate buffer
3. Carbonic acid- Bicarbonate system buffer
4. Hemoglobin system buffer
5. None
Pepsinogen, the inactive form of pepsin, is secreted by:
1. Interstitial cell of Cajal
2. Chief cell
3. Paneth cell
4. Goblet cell
5. Zymogen Cells
Type IIB muscle fibers are different from type I fiber with having:
1. Small diameter
2. Calcium reWlease by sarcoplasmic reticulum is low
3. Fast fatigable
4. Color pink
5. Faster acting
Which of the following is true about myoglobin:
1. Bind 1 mol of oxygen per mole of myoglobin
2. Dissociation curve is a rectangular hyperbola
3. Its curve lies right of the hemoglobin curve
4. Bind oxygen at low P02 pressure
5. Show Bohr effect
Vasomotor inputs to rostral nuclesus of ventomedial medulla is/are from:
1. Inhibitory input from caudal ventrolateral medulla
2. Excitatory inputs from cerebral cortex via hypothalamus
3. Inhibitory inputs from cerebral cortex via hypothalamus
4. Inhibitory inputs from brain stem reticular formation
5. Inhibitory inputs pain pathway

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For Growth hormone testing, which of the following stimulate the secretions of Growth hormone:
1. Glucagon
2. Insulin
3. Cortisol
4. Water deprivation
5. Arginine
Which of the following are feature of blood-brain barrier:
1. Thick basement membrane
2. Podocyte
3. Closely associated layer of astrocyte
4. Tight junction
5. Decreased vesicles in endothelial cells
Which of the following statement is/are true regarding Fick principle of measurement of cardiac output:
1. Cardiac output is calculated by amount of oxygen consumed by whole body per unit mass divided by A-V Oxygen difference across the lung
2. Oxygen concentration in artery is measured by passing catheter to Pulmonary artery
3. Mixed venous blood is measured by inserting catheter into pulmonary artery
4. Rate of oxygen absorption by the lungs is measured by spirometry
5. For oxygen content of artery, any artery of body can be chosen
Feature (s) of hyperprolactinemia is/are all except:
1. Amenorrhoea
2. Decrease milk production
3. Galactorrhoea
4. Hypogonadotropic hypogonadism
5. Hypothyroidism may cause hyperprolactinemia
Which of the following is/are Pain scale:
1. McGill Pain Questionnaire
2. Visual analogue scale
3. Coloured Analogue Scale
4. All of the above
5. None of the above

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True about Oxytocin:
1. Secreted from anterior pituitary
2. Secreted by posterior pituitary
3. Decapeptide
4. Gonadotropin releasing hormone (GnRH) stimulate its secretion
5. Cause milk ejection by contraction of myoepithelium of breast
True about hormone sensitive lipase:
1. Activity is increased by insulin
2. Found intracellular
3. Activated by Epinephrine
4. Located in wall blood capillaries
5. None
Which of the following is true regarding GLUT-5:
1. Present in brain
2. Present in Adipose tissue, skeletal muscle & skin
3. Insulin mediated transporter
4. Sodium independent transport
5. Present in RBC
True statement relating to compliance of lung:
1. Increased by surfactant
2. Decreased in emphysema
3. At height of inspiration compliance is less
4. It can be measured by measuring intrapleural pressure at different lung volume
5. None
True about Hering-Breuer reflex:
1. Signal initiated through mechanoreceptor receptors of lung
2. Signal initiated through Chemoreceptor of lung
3. Signal initiated through Carotid & aortic body
4. Transmit signals through the vagus nerve
5. None

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True about blood supply of kidney:
1. Flow is 600 ml/min each kidney
2. It receives more blood supply per unit mass than the brain
3. Renal medulla have more supply than renal cortex
4. It is under direct sympathetic control
5. None
All are true about Brunner's gland except:
1. It lies in duodenum only
2. It lies in duodenum & ileum
3. It secretes bicarbonate rich fluid
4. It secretions neutralizes acidic pH of stomach
5. Secretes mucus rich fluid
Oxygen binding to hemoglobin cause allosteric activation. This allosteric property of Hb results in :
1. Maintaining iron in ferrous state (Fe2+)
2. Increase oxygen supply to tissue
3. Increases oxygen binding
4. Increases 2,3-DPG in blood
5. None
Calcitriol in children is formed in:
1. Glomerulus
2. Bowmann capsule
3. PCT
4. DCT
5. Collecting duct
Secretion of insulin is increased by:
1. Fatty acid
2. Aminoacid
3. Adrenaline
4. Acetylcholine
5. Somatostatin

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True about carbohydrate metabolism:
1. It supplies 4 kcals per gram
2. It increases insulin secretion
3. Stored in liver
4. In starvation glycogen in liver is exhausted only after 24-48 hr
5. It provide 80% calorie need of body
Nerve velocity is increased by:
1. Myelination
2. Smaller axon diameter
3. Decreased temperature
4. Increase in intracellular calcium
5. Increase in extracelluar sodium

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This download link is referred from the post: PGI Chandigarh Last 10 Years 2011-2021 Solved Question Papers (PGIMER Previous Papers)

This post was last modified on 11 August 2021