Download KUHS MBBS First Year 2012 Aug 106001 Biochemistry Paper II Question Paper

QP Code 106001

First Professional MBBS Degree Examinations, August 2012

BIOCHEMISTRY - PAPER II

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Time: 3 hrs Max marks : 50

• Answer all questions
• Draw diagrams wherever necessary

Essay (10)

1. Describe the sources, RDA, biochemical functions and deficiency manifestations of vitamin D. (2+1+5+2=10)

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Short essays (2x5=10)

2. Describe the salvage pathway of purine nucleotide synthesis with its significance. Describe the disorder associated with it.
3. Describe the structure and functions of tRNA.

Short notes (5x3=15)

4. Define metabolic acidosis. Mention the causes and biochemical finding in metabolic acidosis.

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5. Define replication and mention four inhibitors of replication.
6. Marasmus.
7. Mention the functions of zinc.
8. Cause and clinical features of acute intermittent porphyria.

Answer briefly (5x2=10)

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9. Define nucleotide. Name two adenosine nucleotide derivatives.
10. Point mutation
11. Name the liver function tests.
12. Functions of biotin.
13. Define thalassemia and mention the different types of thalassemias.

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Give precise answers (5x1=5)

14. Name two tumor suppressor genes.
15. Define genetic code.
16. Name two hormones causing increased levels of cyclic AMP.
17. Name the coenzyme required for transamination reactions.

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18. Mention the normal serum calcium level.

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