Q.P.Code 1601
First Professional MBBS Degree Supplementary Examinations - March 2012
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BIOCHEMISTRY- PAPER II
Time: 3 hrs Max marks: 50
- Answer all questions
- Draw diagrams wherever necessary
Essay (10)
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- Describe about sources, RDA, biochemical functions and deficiency manifestations of vitamin A. (1+1+6+2=10)
Discuss the following: (2x5=10)
- Define protein energy malnutrition and compare marasmus and kwashiorkor
- Describe the salvage pathway of purine nucleotide synthesis with its significance. Describe the disorder associated with it.
Write short notes on: (5x3=15)
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- Describe any four functions of calcium
- Structure of DNA
- Define metabolic acidosis. Mention the causes and biochemical finding in metabolic acidosis.
- Define Reverse transcription and mention its significance
- Name the tests to measure GFR and define creatinine clearance.
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Answer briefly: (5x2=10)
- Mention few unusual bases and mention where it is present.
- Name the buffer systems in the body.
- Mention the cause and clinical features of pellagra.
- What is gout and mention few clinical features of gout.
- Mention two diagnostic uses of radioactive isotopes.
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Give precise answers: (5x1=5)
- Name the hormones causing increased cyclic AMP production.
- Enzyme used as tumor marker.
- Mention the normal level of serum creatinine.
- Mention the enzyme deficient in severe combined immunodeficiency disorder.
- What type of mutation occurs in sickle cell anemia and what is the biochemical defect in sickle cell anemia.
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