QP Code 1601 Reg. No.:........................
First Professional MBBS Degree Examinations - September 2011
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BIOCHEMISTRY - PAPER II
Time : 3 hrs Max marks : 50
- Answer all questions
- Draw diagrams wherever necessary
Essay (10)
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- Describe how protein is synthesized in body. Name any two inhibitors of protein biosynthesis. Add a note on post translational modifications. (6+2+2=10)
Discuss the following: (2x5=10)
- Outline the degradation of heme. Add a note on fate of conjugated bilirubin in intestine.
- Write briefly on storage and absorption of iron from intestine.
Write short notes on: (5x3=15)
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- What is gout. Mention the causes of primary gout.
- What is the role of kidney in acid base regulation.
- What are restriction endonucleases. What are their uses.
- Write principle and application of polymerase chain reaction.
- Write the structure of IgG molecule and indicate its function.
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Answer briefly: (5x2=10)
- Name the coenzyme forms of niacin and write important functions for each one of them.
- Wilson's disease.
- What is metabolic acidosis. Give one example of a disease associated with it.
- Give two examples of detoxification by conjugation.
- What is post hepatic jaundice. How is it diagnosed biochemically.
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Give precise answers: (5x1=5)
- What is provitamin. Give one example.
- Clinical features of rickets.
- Give one example for point mutation.
- What are the enzymes commonly used in ELISA Technique.
- Xeroderma pigmentosum is due to deficiency of what process.
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