KUHS MBBS Second Year Last 17 Years 2007-2024 Previous Question Papers
Q.P. Code: 201001
Reg. no.: ........................
Second Professional MBBS Degree Examinations February 2018
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Pharmacology- Paper I
Time: 2 Hours
Total Marks: 40
- Answer all questions
- Draw diagrams wherever necessary
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Essays: (2x6=12)
- Classify antihypertensive drugs. Describe the mechanism of action, uses and adverse effects of angiotensin converting enzyme (ACE) inhibitors. (2+2+1+1)
- Sarala, 28 years old lady was suffering from depression. The physician prescribed tablet fluoxetine 20mg/day for her. Answer the following:
- What is the mechanism of action of fluoxetine.
- What is the advantage of this drug compared to tricyclic antidepressants.
- What can happen if this patient is administered pethidine concurrently (2+2+2)
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Short notes: (5x3=15)
- Plasma half life
- Edrophonium
- Sumatriptan
- Propofol
- Clopidogrel
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Answer briefly: (5x1=5)
- Tachyphylaxis. Give examples
- Why is benzhexol used in the treatment of drug induced Parkinsonism.
- Explain the use of propranolol in thyrotoxicosis.
- Rationale of using low dose aspirin in post myocardial infarction.
- Atracurium
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Name two drugs: (8x1=8)
- Available as transdermal patch
- Used in the treatment of atrial fibrillation
- Potassium sparing diuretics
- Used in treatment of acute congestive glaucoma
- Histamine releasers
- In treatment of absence seizures
- Fibrinolytic agents
- Disease modifying anti-rheumatic drugs
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