Q.P. Code: 201001
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Reg. no.: ....................
Second Professional MBBS Degree Supplementary Examinations, August 2017
Pharmacology- Paper I
Time: 2 Hours | Total Marks: 40 |
- Answer all questions
- Draw diagrams wherever necessary
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Essays: (2x6=12)
- Enumerate five groups of anti-hypertensive drugs with examples of each. Discuss the mechanism of action, adverse effects and therapeutic uses of any one of them. (2+2+1+1)
- Read the clinical problem and answer the following questions:
- After injection of succinylcholine i.v. to provide muscle relaxation, the patient developed prolonged apnoea.
- What is the probable reason for this.
- Can edrophonium be given as antidote. If yes, why and if not why not.
- What is the line of treatment. (2+2+2=6)
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Short notes: (5x3=15)
- Neostigmine.
- Propofol.
- Clopidogrel.
- Physiological antagonism.
- Furosemide.
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Answer briefly: (5x1=5)
- Two advantages and two disadvantages of i.v. route of drug administration.
- Explain the rationale for the use of oximes in organophosphorus poisoning.
- Mechanism of action of nitrates.
- Explain the pharmacological basis for the use of ethyl alcohol in methanol poisoning.
- Mention two selective Cox-2 inhibitors.
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Name two drugs: (8x1=8)
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- Pro drugs
- H1 receptor blockers
- Anti-muscarinic drugs
- Teratogenicity
- Treatment of Iron deficiency anemia
- Selective alpha blockers
- Selective serotonin reuptake inhibitors
- Pre-anesthetic medication
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