Download KUHS MBBS 2nd Year 2017 July 202001 Pharmacology Paper Ii Question Paper

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Q.P. Code: 202001 Reg. no.: .........................

Second Professional MBBS Degree Supplementary Examinations, August 2017

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Pharmacology- Paper II

Time: 2 Hours Total Marks: 40

Essays: (2x6=12)

• Answer all questions
• Draw diagrams wherever necessary

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1. Classify oral hypoglycemic agents. Explain the mechanism of action and adverse effects of any one group. (2+2+2)
2. A 20 years old pregnant women developed a mild bacterial upper respiratory tract infection. She was given cap. tetracycline 250 mg thrice daily for 3 days. Answer the following questions:
   • Comment on the treatment for a mild bacterial infection
   • Comment on the use of tetracycline in pregnancy
   • If it were a severe infection what would be the choice of antibiotic in a pregnant woman. (2+2+2)

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Short notes: (5x3=15)

3. 4^th generation cephalosporins
4. Metronidazole
5. Chloroquine
6. Bisphosphonates

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7. Clomiphene citrate

Answer briefly: (5x1=5)

8. Mechanism of action of INH
9. Rationale for the use of combination of drugs in cancer chemotherapy
10. Pharmacological basis for the use of thalidomide in lepra reaction

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11. Anti- thyroid drugs safe during pregnancy
12. Rationale for the use of folinic acid in methotrexate overdose

Name two drugs: (8x1=8)

13. Treatment of MDR-TB
14. Post exposure prophylaxis of HIV (acquired immunodeficiency syndrome)

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15. Treatment of acne vulgaris
16. Prophylaxis of rheumatic fever
17. Insulin analogues
18. Proton pump inhibitors
19. Topical antifungal agents

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20. Anabolic steroids

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