Rajiv Gandhi University of Health Sciences, Karnataka
I Year B.Pharm Degree Examination - 05-Jun-2024
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Time: Three Hours Max. Marks: 70 Marks
PHARMACEUTICAL ORGANIC CHEMISTRY - I (RS-3)
Q.P. CODE: 2604
Your answers should be specific to the questions asked
Draw neat labeled diagrams wherever necessary
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LONG ESSAYS (Answer any Two) 2 x 10 = 20 Marks
- Explain the mechanism of 1, 2-and 1, 4-addition to conjugated dienes. Write the effect of temperature on 1, 2-and 1, 4-addition.
- Halogens are deactivators, yet ortho-para directors. Justify with relevant examples with mechanism.
- Write the mechanism of Aldol condensation and Kolbe’s reaction.
SHORT ESSAYS (Answer any Six) 6 x 5 = 30 Marks
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- Write a note on Hyper conjugation.
- What is hydrogen bonding? Discuss its applications.
- What is Diels Alder reaction? Write its mechanism.
- Write a note on acidity of carboxylic acids with effect of substituent’s on the acidity.
- How the diazo group is replaced? Write the mechanism of Sandmeyer’s reaction.
- What happens when methane is allowed to react with chlorine in presence of light? Give its mechanism.
- Discuss the stability of conjugated dienes.
- Write the mechanism of Fries arrangement.
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SHORT ANSWERS 10 x 2 = 20 Marks
- What is Tautomerism?
- What are carbenes? How they are generated?
- What is Smith reaction?
- What is carbanion?
- Write the structure of 2-propanol and ethanal.
- How benzoic acid is converted to benzoyl chloride? Give reaction.
- What is Williamson’s synthesis? Give examples.
- Define resonance and resonance energy.
- What is Beckmann’s rearrangement?
- What is Claisen condensation?
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This download link is referred from the post: RGUHS B.Pharmacy 1st Year 2014-2024 Last 10 Years Previous Question Papers (B.Pharm Latest Papers))
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