Download RGUHS B.Pharm 1st Year 2021 March 2604 Pharmaceutical Organic Chemistry I Revised Scheme 3 Question Paper

Download RGUHS?(Rajiv Gandhi University of Health Sciences) B.Pharmcy (Bachelor of Pharmacy) 1st Year (First Year) 2604 Pharmaceutical Organic Chemistry I Revised Scheme 3 Previous Year Question Paper

Rajiv Gandhi University of Health Sciences, Karnataka
I Year B.Pharm Degree Examination ? 23-Mar-2021
Time: Three Hours





Max. Marks: 70 Marks
PHARMACEUTICAL ORGANIC CHEMISTRY ? I
(Revised Scheme 3)
Q.P. CODE: 2604
Your answers should be specific to the questions asked
Draw neat labeled diagrams wherever necessary
LONG ESSAYS (Answer any Two)
2 x 10 = 20 Marks
1.
Discuss `E1 and E2' reaction with mechanism, kinetics and orientation
2.
Explain the addition of HBr to 1,3 ? butadiene with mechanism & orientation
3.
Explain (a) Cannizaro reaction (b) Beckmann's rearrangement
SHORT ESSAYS (Answer any Six)
6 x 5 = 30 Marks
4.
Explain the conversion of carboxylic acid into (a) Acid chloride, (b) Amide (c) Ester
(d) Anhydride
5.
Explain NO2 group is deactivating & m?directing but NH2 group is activating & o-directing in
aromatic electrophilic substitution reaction.
6.
Explain the nitration of Benzene
7.
Write a note on chlorination of methane
8.
Write short note on reactivity of alkyl halides towards SN1 reaction
9.
What are cycloalkanes? Write any three methods of preparation of cycloalkanes.
10. Write a note on Diel's Alder reaction
11. Explain the basicity of various amines & effect of substituents on basicity
SHORT ANSWERS
10 x 2 = 20 Marks
12. What are Carbenes? Give example
13. Why o ?nitrophenol is steam volatile but p-nitrophenol is not?
14. Kharasch peroxide effect
15. Write the structures of (a) 2-butenoic acid (b) 2-chloro-2-pentene
16. Example of stereochemical inversion
17. Dipole moment
18. Reimer Tiemann reaction
19. Isomerism
20. Name the electrophiles used in Friedel Craft alkylation and sulphonation of benzene
21. Diazotization
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