Download RGUHS B.Pharm 1st Year 2021 November 1954 Pharmaceutical Organic Chemistry I Revised Scheme 2 Question Paper

Download RGUHS?(Rajiv Gandhi University of Health Sciences) B.Pharmcy (Bachelor of Pharmacy) 1st Year (First Year) 1954 Pharmaceutical Organic Chemistry I Revised Scheme 2 Previous Year Question Paper

Rajiv Gandhi University of Health Sciences, Karnataka
I Year B.Pharm Degree Examination ? 17-Nov-2021

Time: Three Hours





Max. Marks: 80 Marks
PHARMACEUTICAL ORGANIC CHEMISTRY - I
(Revised Scheme - 2)
Q.P. CODE: 1954
Your answers should be specific to the questions asked
Draw neat labeled diagrams wherever necessary
LONG ESSAYS (Answer any Two)
2 x 10 = 20 Marks
1.
Define aromatic Electrophilic substitution reactions. Discuss the reaction mechanism of
nitration and sulphonation.
2.
Define elimination reaction. Discuss the mechanism of E1 and E2 reaction with suitable
example.
3.
Define and give the mechanism of following reactions
(i) Aldol condensation (ii) Benzoin condensation
SHORT ESSAYS (Answer any Eight)
8 x 5 = 40 Marks
4.
Explain the Bayer's strain theory of cycloakanes.
5.
Define Nucleophilic aliphatic substitution reaction? Give the mechanism of SN1 reaction.
6.
Define and give the mechanism of Cannizzaro reaction.
7.
What is electrophillic addition reaction and give the mechanism of Markovnikov's addition.
8.
Write a note on acidity of phenols.
9.
Explain the mechanism of Curtius reaction.
10. Give one method each for the conversion of carboxylic acid into acid anhydride, acid amide and
acid chloride.
11. Explain Friedel crafts acylation reaction.
12. Write chlorination of methane with mechanism.
13. Write a note on dehydration of alcohols.
SHORT ANSWERS
10 x 2 = 20 Marks
14. Define the terms "Polarity" and "Polar aprotic solvent.
15. What is hydrogen bond? Give two example showing hydrogen bonding.
16. Give the structure and uses of (i) Aspirin (ii) Dimercaprol
17. Define electrophiles with examples.
18. What is diazotization reaction? Give an example.
19. How do you synthesize ester from carboxylic acid?
20. What is a carbocation? Give an example
21. Define ring activating and deactivating group with examples
22. Define acids and bases according to Bronsted-Lowry and Lewis theory.
23. Define Keto-enol tautomerism.
*****

---