Rajiv Gandhi University of Health Sciences, Karnataka
I Year B.Pharm Degree Examination — 23-Nov-2022
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Time: Three Hours Max. Marks: 70 Marks
PHARMACEUTICAL ORGANIC CHEMISTRY - I (RS3)
Q.P. CODE: 2604
Your answers should be specific to the questions asked
Draw neat labeled diagrams wherever necessary
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LONG ESSAYS (Answer any Two) 2 x 10 = 20 Marks
- Discuss the nucleophilic aliphatic substitution reactions emphasizing the mechanism and orientation
- Explain with examples and mechanism :
- Perkin’s reaction
- Reimer Tiemann reaction
- Cannizzaro’s reaction
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- Explain with examples and mechanisms
- Free radical substitution to alkanes
- Free radical addition to alkenes
- Electrophilic addition to alkenes
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SHORT ESSAYS (Answer any Six) 6 x 5 = 30 Marks
- Give the kinetics and mechanism of E1 and E2 reactions
- Explain Lowry-Bronsted theory of acids and bases
- Explain the stability of conjugated dienes
- Give the mechanism involved in the following reactions
- Claisen condensation
- Hofmann’s reaction
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- Explain the theory of orientation by amino/group and chlorine in electrophilic aromatic substitution
- Discuss the mechanism of dehydration of alcohols and comment on the orientation
- What are alkenes? Give the rules for the nomenclature of alkenes with examples
- Discuss Williamson’s synthesis, its applications and limitations
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SHORT ANSWERS 10 x 2 = 20 Marks
- How do substituents influence the acidic strength of phenols
- How do you synthesis m-bromonitrobenzene from benzene?
- Give IUPAC names for
- CH3—CH2-CH2-COOH
- HC=C-CH-CH=CH2
|
CH3
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- Distinguish between protic and aprotic solvents give examples
- How do you prepare diazonium salts? Give the reaction involved
- What is functional and position isomerism? Give examples.
- Give examples for Friedel craft’s alkylation and acylation
- Define carbonium ion, classify with examples.
- Write examples of a cycloaddition reaction
- Write a note on Huckel’s rule of aromaticity
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This download link is referred from the post: RGUHS B.Pharmacy 1st Year 2014-2024 Last 10 Years Previous Question Papers (B.Pharm Latest Papers))
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