Download MBBS (Bachelor of Medicine and Bachelor of Surgery) Portal Hypertension PowerPoint PPT presentation
Portal hypertension is defined as the elevation of
hepatic venous pressure greadient to>5mmHg
Clinically significant portal hypertension
HVPG>10mmHg
Risk of variceal bleeding increases beyond a gradient
of 12mmHg
Classification
PRE-HEPATIC
portal vein thrombosis
splenic vein thrombosis
massive splenomegaly
Classification..
HEPATC
? 1.Pre sinusoidal
schistisomiasis
congenital hepatic fibrisis
2.Sinusoidal
cirrhosis
alcoholic hepatitis
3.Post sinusoidal
hepatic sinusoidal obstruction
Classification...
POST-HEPATIC
Budd-Chiari syndrome
Inferior venacaval webs
cardiac causes:
restrictive cardiomyopathy
constrictive pericarditis
severe congestive heart failure
Pathophysiology
The fundamental haemodynamic abnormality is
increased resistance to portal blood flow
Results in development of collateral circulation that
diverts obstructed bloodflow to systemic veins
Clinical features
Ascitis
Increased portosystemic shunt
oesophageal varices
haemorrhoids
caput medusae
Hypersplenism
Hepatic encephalopathy
Hepatorenal failure
Thank you..
This post was last modified on 12 August 2021