Download KUHS MBBS 1st Year 116001 Biochemistry Paper II 2023 February 2019 Scheme Question Paper

Q.P. Code: 116001

2019 Scheme

Reg. no.: ........................

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First Professional MBBS Degree Regular/Supplementary Examinations

February 2023

Biochemistry - Paper II

Time: 3 Hours

Total Marks: 100

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• Answer all questions to the point neatly and legibly. Do not leave any blank pages between answers.
• Indicate the question number correctly for the answer in the margin space
• Answer all parts of a single question together. Leave sufficient space between answers
• Draw table/diagrams/flow charts wherever necessary

Long Essays (2x15=30)

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1. 35-year-old female, housewife, presented to the medicine department with excessive weakness, breathlessness and palpitations since 3 months. History revealed that she had complaints of excessive menstrual bleeding. She had followed strict vegetarian diet. Investigations revealed her hemoglobin was 7 Gms/dL
   1. What is the probable diagnosis (1)
   2. Describe the sources, RDA, functions, absorption, transport and deficiency of the mineral involved (1+1+3+3+2)
   3. Describe the biochemical investigations and blood picture relevant to this case (4) (1+11+3)
2. Definition, steps and inhibitors of translation (5x8=40)

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Short essays

3. Diagrammatically represent the structure of tRNA. Describe the functions of tRNA (4+4)
4. Principle and applications of Beer-Lamberts law. Add a note on colorimetry (3+5)
5. Classify renal function tests. Describe clearance tests in detail (5+3)
6. Describe PCR and its applications. Add a note on its significance in diagnosis of covid-19 (4+2+2)

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7. Discuss the structure and functions of immunoglobulin. Add a note on monoclonal antibodies (4+2+2)

Short answers (5x4=20)

8. Contractile proteins
9. Mucosal block theory
10. Salvage pathway

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11. Effects of free radicals
12. Detoxification by conjugation

Give Precise Answers (10x1=10)

13. Biochemical defect in orotic aciduria
14. Disease associated with DNA repair

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15. What is a telomere
16. Function of calcium responsible for prevention of tetany
17. Western blot
18. Reverse transcriptase
19. Benzoic acid, a food preservative, is detoxified by________

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20. Two causes for respiratory acidosis
21. Microalbuminuria
22. Two functions of magnesium

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