MBBS: Biochemistry Paper 2 Part 1.
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ABVMUUPPaper Code: 2122130003
Q1. Give a detailed account of the transcription process. How is it regulated? Name inhibitors of transcription. (20 marks)
Q2. (4 x 5 = 20 marks)
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Write briefly on:
(a) Multiple myeloma
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(b) GTT(c) Mutations
(d) Genetic code
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Q3. Multiple Choice Questions: (Each question carries 1 mark = 10)
- a. Gene amplification can be achieved by:
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A) Southern blotting
B) DNA finger printing
C) Polymerase chain reaction--- Content provided by FirstRanker.com ---
D) Gene cloning - b. All the following are nucleic acids, EXCEPT:
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A) Plasmids
B) Prions
C) Cosmids--- Content provided by FirstRanker.com ---
D) Virons - c. Negative nitrogen balance is observed in:
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A) Pregnancy
B) Chronic fever
C) Convalescence--- Content provided by FirstRanker.com ---
D) Growth period - d. Which enzymes protects DNA from ageing?
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A) DNA polymerase
B) Topoisomerase
C) Deoxyribonuclease--- Content provided by FirstRanker.com ---
D) Telomerase - e. Serum alkaline phosphatase is increased in:
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A) Hypothyroidism
B) Carcinoma of prostate
C) Bone diseases--- Content provided by FirstRanker.com ---
D) Myocardial infarction - f. Proximal renal tubular acidosis is characterized by all, EXCEPT:
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A) Metabolic acidosis
B) Normal anion gap
C) Urine pH of 4.5--- Content provided by FirstRanker.com ---
D) Hyperchloremia - g. Which is the anticoagulant of choice for biochemical estimation in general:
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A) EDTA
B) Oxalate-flouride mixture
C) Lithium heparin--- Content provided by FirstRanker.com ---
D) Citrate - h. Which anions are present in normal urine:
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A) Phosphate
B) Sulfate
C) Chloride--- Content provided by FirstRanker.com ---
D) Proteinate - i. A patient with infective hepatitis is likely to have all the following findings, except:
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A) Hyperbilirubinemia
B) Bilirubinuria
C) Absence of bile salts in urine--- Content provided by FirstRanker.com ---
D) Elevated AST - j. All the techniques listed below measures proteins, except:
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A) Nephelometry
B) Flame photometry
C) ELISA--- Content provided by FirstRanker.com ---
D) Radial immunodiffusion
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Biochemistry Paper 2 Part 2.
ABVMUUP
Paper Code:2122230003
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Q1. What are xenobiotics? Describe the role of glutathione in detoxification. (20 marks)
Q2. Write short notes on: (5 marks each = 20)
- Maple syrup urine disease
- Gonadotropins
- Oncogenes
- Visual cycle
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Q3. Multiple choice questions: (Each question carries 1 mark: Total 10 marks)
- a. In human body, highest concentration of ascorbic acid is found in:
A) Liver
B) Adrenal cortex--- Content provided by FirstRanker.com ---
C) Posterior pituitary gland
D) Muscle - b. The metal present in vitamin B12 is:
A) Copper
B) Cobalt--- Content provided by FirstRanker.com ---
C) Chromium
D) Manganese - c. Alpha-fetoprotein level in serum is increased in:
A) Prostatic cancer
B) Hepatoma--- Content provided by FirstRanker.com ---
C) Lung cancer
D) Nephritis - d. Name the defective enzyme in phenylketonuria:
A) Cystathionase
B) Phenylalanine hydroxylase--- Content provided by FirstRanker.com ---
C) Homogentisic acid oxidase
D) Para-hydroxyphenylpyruvate oxidase - e. Nutritional status of a person can be assessed by all, EXCEPT:
A) Serum protein estimation
B) Hemoglobin level--- Content provided by FirstRanker.com ---
C) Gain or loss in weight
D) Mid, arm circumference - f. Features of galactosemia include the following, EXCEPT:
A) Cataract
B) Hepatosplenomegaly--- Content provided by FirstRanker.com ---
C) Mental retardation
D) Hemolytic anemia - g. Sunlight helps maximally in the synthesis of which of the following vitamin in the body:
A) Vitamin A
B) Vitamin B--- Content provided by FirstRanker.com ---
C) Vitamin C
D) Vitamin D - h. All the following are characteristics of thalassemia major, EXCEPT:
A) It is manifested when the affected genes are in homogenous state
B) It is the result of gene deletion--- Content provided by FirstRanker.com ---
C) It is a common molecular disease In India
D) It is incompatible with life - i. Nyctalopia (abnormal inability to see in dim light) Is due to the deficiency of:
A) Vitamin K
B) Vitamin E--- Content provided by FirstRanker.com ---
C) Vitamin B12
D) Vitamin A - j. Steroid hormones are produced from:
A) Purine
B) Pyrimidine--- Content provided by FirstRanker.com ---
C) Cholesterol
D) Stercobilinogen
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Sat, 28th May 2022 Max marks 50