KGMU-Jan 2022
MBBS 2nd PROFESSIONAL EXAMINATION, 2022
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MICROBIOLOGY
Paper I
Time Allowed: Three Hours
Maximum Marks- 100
Note: Attempt all questions in serial order. Answer Section-A and Section-B in separate answer books. All parts of a question should be answered together. Illustrate your answer with suitable diagram where required. Figures in parenthesis indicate marks allotted to a question.
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Section-A
Q1. Enumerate the various methods of horizontal gene transfer. Discuss in detail about mechanism of conjugation. (20)
Q2. Write briefly on: (4x5)
- Classical Complement pathway
- Disposal of microbiology laboratory waste
- Autoclave
- Prozone phenomenon
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Q3. Multiple Choice Questions: (10x1)
- Polymerase chain reaction (PCR) was discovered by:
- Kary B Mullis
- Goodpasture
- Robert Koch
- Edward Jenner
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- What is optimal temperature for growth of mesophilic bacteria?
- Below 20°C
- 25-40°C
- 55-80°C
- None of the above
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- Loeffler'S serum slope is an example of:
- Differential medium
- Enriched medium
- Selective medium
- None of the above
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- Which of the following are true for bacterial plasmid EXCEPT
- They are extrachromosomal
- They cannot replicate independently
- They are not essential for bacterial life
- They usually carry important genetic information
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- All of the following are heterophile agglutination tests Except:
- Weil Felix reaction
- Paul Bunnel test
- Cold agglutination test
- Widal test
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- All of the following immunoglobulins are heat stable Except:
- IgM
- IgG
- IgE
- IgA
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- Firstranker's choiceGella is found in which of the following bacteria:
- Escherichia coli
- Vibrio cholera
- Pseudomonas
- Campylobacter
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- UV rays are used for disinfection of all the following except:
- Operation theaters
- Laminar flow hoods
- Water treatment
- Disposable plastic syringes
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- All of the following are TRUE about exotoxins Except:
- They are heat labile proteins
- They are poorly antigenic
- Neutralised by specific antibodies
- They are secreted both by gram-positive and negative bacteria
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- Southern blotting is used for detection of which of the following?
- DNA
- RNA
- Proteins
- None
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Section-B
Q1. Write pathogenesis, diagnosis and management of typhoid fever. (20)
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Q2. Write short notes on: x6)
- Toxic shock syndrome
- Nongonococcal urethritis-
- Non-typhoidal Salmonella
- Bacillary dysentery -
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Q3. Multiple Choice Questions: (10x1)
- All of the following are toxin-mediated Staphylococcus aureus diseases Except:
- Osteomyelitis
- Food poisoning
- Toxic Shock Syndrome
- Staphylococcal scalded skin syndrome
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- All of the following are true about Streptococcus pneumonia EXCEPT:
- They are capsulated diplococcic
- They ferment Inulin
- They are optochin sensitive
- They are bile insoluble
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- Diphtheria toxin is/are produced by following Corynebacterium species:
- C. diptheriae
- c. ulcerans
- C. pseudotuberculosis
- All of the above
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- Pink eye and Brazilian purpuric fever are caused by:
- H. aegyptius
- H. influenzae
- H. aphrophilus
- H. ducreyi
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- FIR FB FirstRanker.com KGMU-Jan 2022 Firstranker's chop the following are true about Brucella Except
- They have preefirsthand praca
- They cause Undulant fever
- Castaneda's method of blood culture is used for isolation of Brucella
- They are gram +ve cocci
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- Rocky Mountain Spotted fever is caused by:
- R. prowazekii
- R. rickettsii
- R. typhi
- O. tsutsugamushi
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- Venereal Syphilis is caused by:
- T. pallidum
- T.pallidum subsp. Endemicum
- T. pallidum subsp.pertenue
- T. carateum
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- All of these mycobacteria cause skin lesions except:
- M. ulcerans
- M. tuberculosis
- M. marinum
- None of the above
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- Food poisoning is caused by:
- Staphylococcus aureus
- Bacillus cereus
- Clostridium perfringens
- All of the above
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- All of the following Vibrio species are halophilic, Except
- Vibrio vulnificus
- Vibrio cholera
- Vibrio parahaemolyticus
- Vibrio alginolyticus
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