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M-0115
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KGMU-Aug 2018
MBBS 2nd PROFESSIONAL EXAMINATION, 2018
PHARMACOLOGY
PAPER I
Time Allowed: Three Hours
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Maximum Marks-40-29
Note:- Attempt all questions in serial order. All parts of a question should be answered together.
Figures in parenthesis indicate marks allotted to a question.
Q1. Define with example:- (5)-3
- Agonist
- First order kinetics
- Idiosyncrasy
- Pharmacovigilance
- Bioavailability
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Q2. Comment on:- (5)-2.5
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- Vasomotor reversal of Dale
- Cheese reaction
- Substitution therapy
- Generic drugs
- Recrudescence
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Q3. Justify the basis of use of:- (5)-3
- Silodosin in BPH
- Ranolazine in myocardial infarction
- Zopiclone in insomnia
- Beclomethasone in bronchial asthma
- Lisinopril in heart failure
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04. Enumerate five rational drug combinations with reasons. (5)-3
05. Classify anti-diabetic agents. How diabetic ketoacidosis is treated? (5)-2.
Q6. A 45 years old patient was diagnosed with MDR pulmonary tuberculosis. Which antitubercular agents can be prescribed and which are avoided and Why? (5) 3
07 Enumerate important uses of:- (5) 2
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- Skeletal muscle relaxants
- Anticholinergics
- Macrolides
- Laxatives
- Anticoagulants
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08. Write one indication, contraindication, adverse drug reaction and drug interaction of:- (5) 3
- Clonidine
- Clopidogrel
- Clozapine
- Clotrimazole
- Clofazimine
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