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Rajiv Gandhi University of Health Sciences, Karnataka
MBBS Phase - II (CBME) Degree Examination - 11-Dec-2024
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Time: Three Hours Max. Marks: 100
MICROBIOLOGY – PAPER I (RS-4)
Q.P. CODE: 1030
(QP contains two pages)
Your answers should be specific to the questions asked
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Draw neat, labeled diagrams wherever necessary
LONG ESSAYS 2 x 10 = 20 Marks
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A 9 year old boy from an overcrowded colony presented to the paediatric emergency department during monsoons with complaints of profuse and frequent watery diarrhoea since the previous day, accompanied by 2-3 episodes of vomiting. On examination, he was found to be moderately dehydrated. The stool on gross examination had a characteristic 'Rice water' appearance.
- What is the probable etiological diagnosis?
- Discuss in detail epidemiology and pathogenesis of the above condition
- Add a note on laboratory diagnosis
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A 30 year old young adult with history of multiple sex partners is admitted with complaints of unexplained fever, weight loss, persistent diarrhoea and generalized lymphadenopathy for past 6 months.
- What is the probable diagnosis?
- Discuss the pathogenesis and laboratory diagnosis of the above condition
- What are the preventive measures for the above infection?
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SHORT ESSAYS 8 x 5 = 40 Marks
- Describe tuberculin type of delayed hypersensitivity.
- Describe classes of major histocompatibility complex and their role in Immunity.
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A child presents with vesicular rashes. Rashes are bilateral, diffuse and centripetal in distribution. Fever appears with each crop of eruption. What is the probable clinical diagnosis & discuss the prevention of this infection
- Differentiate eumycotic mycetoma from actinomycotic mycetoma
- Sequence of events that occur following entry of quadri-nucleate cyst of Entamoeba histolytica into the gut
- Describe the pathogenesis and the laboratory diagnosis of lepromatous leprosy.
- Diarrheagenic Escherichia coli
- Describe the differences between resistance acquired by mutation and transferrable drug resistance
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SHORT ANSWERS 10 x 3 = 30 Marks
- Morphological classification of fungi with examples
- Name three bacterial causes of food poisoning
- Name three infections produced by Staphylococcus aureus.
- What is occult filariasis?
- Name three opportunistic sporozoa that cause diarrhea
- Name three non-albicans species of Candida
- List three Complications of falciparum malaria
- Type and schedule of Hepatitis B vaccine
- What are sequestered antigens? Give examples
- List differences between active immunity and passive Immunity
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Rajiv Gandhi University of Health Sciences, Karnataka
Multiple Choice Questions 10 x 1 = 10 Marks
- Which of the cells are not associated with immune mechanisms?
- Basophils
- Dendritic cells
- Mast cells
- Epithelial cells
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- Tinea versicolor is caused by
- Candida albicans
- Trichophyton rubrum
- Trichophyton violaceum
- Malassezia furfur
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- False statement about dermatophytes
- Fungi that affect the keratinized layer of the skin
- Fungi affecting hair and nail
- They may be geophilic
- They do not grow at room temperature
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- Weil Felix reaction is based on
- Auto specificity
- Iso specificity
- Species specificity
- Heterogenic specificity
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- All of these are antigen presenting cells EXCEPT
- T cells
- B cells
- Dendritic cells
- Macrophage
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- During which of the following phases bacteria are most susceptible to antibiotics?
- Lag Phase
- Log phase
- Stationary phase
- Phase of decline
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- Who is the father of antiseptic surgery
- Robert Koch
- Paul Ehrlich
- Joseph Lister
- Alexander Fleming
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- During first week of enteric fever, salmonellae can be isolated from all EXCEPT
- Bone marrow
- Blood
- Duodenal aspirate
- Urine sample
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- Babesiosis is transmitted by bite of
- Anopheles mosquito
- Sandfly
- Mite
- Tick
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- Causative agent of Calabar swelling is
- Dracunculus medinensis
- Wuchereria bancrofti
- Brugiya malayi
- Loa loa
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