QP CODE : 1028
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Rajiv Gandhi University of Health Sciences, Karnataka
MBBS Phase - II (CBME) Degree Examination - 11-Apr-2025
Time: Three Hours Max. Marks: 100 Marks
PHARMACOLOGY – PAPER I (RS-4 & RS-5)
Q.P. CODE: 1028
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(QP contains two pages)
Your answers should be specific to the questions asked
Draw neat, labeled diagrams wherever necessary
LONG ESSAYS 2 x 10 = 20 Marks
- Define Bioavailability. Discuss various factors that affect Bioavailability
- A 22 year old unresponsive and unconscious man is brought to hospital. His heart rate is 60 per minute, blood pressure is 90/60 mm of Hg and respiratory rate is 10 per minute. He has pinpoint pupils. The treating doctor made a diagnosis of Morphine poisoning.
- Write the drug treatment for Morphine poisoning
- Write the central nervous system actions, therapeutic uses and adverse effects of morphine
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SHORT ESSAYS 8 x 5 = 40 Marks
- Adverse effects and contraindications of beta blockers
- Methods of prolonging drug action
- Discuss the management of organophosphorous Poisoning
- Therapeutic uses of atropine substitutes
- Disease Modifying Anti-Rheumatoid Drugs (DMARDs)
- Inhalational glucocorticoids used in Bronchial Asthma
- A 40 year old businessman presents with complaints of dyspepsia and epigastric pain. Endoscopy revealed Peptic ulcer. He was prescribed pantoprazole.
- Explain the rationale of using pantoprazole in this patient.
- Write its uses and adverse effects
- A 45 year old man presents with sad mood, low energy and loss of interest and pleasure. The psychiatrist diagnosed him to be suffering from depression and prescribed Fluoxetine.
- Explain the rationale of using fluoxetine in this patient.
- Write its other therapeutic uses and adverse effects.
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SHORT ANSWERS 10 x 3 = 30 Marks
- Explain the term first order kinetics with an example
- Rationale of using latanoprost in Glaucoma
- What is diffusion Hypoxia? How is it prevented?
- Explain the rationale of using Diazepam in Insomnia
- Rationale of combining Lignocaine with Adrenaline
- Mention three disadvantages of using Liquid Paraffin as a Purgative
- Rationale of using Paracetamol in fever
- Write three mucolytics
- Explain the concept of Essential medicines (drugs)
- Write three uses of d-Penicillamine
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Page 1 of 3
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QP CODE: 1028
Rajiv Gandhi University of Health Sciences, Karnataka
Multiple Choice Questions 10 x 1 = 10 Marks
- Which of the following receptor is located intracellularly
- Opioid receptor
- Steroid receptor
- Dopamine receptor
- GABA receptor
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- Nicotinic receptor is
- Ligand gated ion channel
- G protein coupled
- Tyrosine kinase linked
- Intra-cellular
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- Propranolol is avoided in which one of the following conditions
- Hypertension
- Ischemic heart disease
- Cardiac arrhythmias
- Bronchial asthma
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- Which of the following is a prodrug of adrenaline used in glaucoma
- Brimonidine
- Dipivefrine
- Phenylephrine
- Pilocarpine
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- The drug useful in the treatment of trigeminal neuralgia is
- Paracetamol
- Carbamazepine
- Aspirin
- Morphine
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- Prolonged treatment with Lithium can cause
- Diabetes mellitus
- Goitre
- Gout
- Rheumatoid arthritis
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- A 35 year old woman is suffering from severe migraine. The migraine gets relieved by sumatriptan. Which drug is appropriate for prophylaxis of migraine?
- Dihydroergotamine
- Ibuprofen
- Propranolol
- Paracetamol
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- Dextromethorphan is an
- Analgesic
- Antitussive
- Expectorant
- Antihistaminic
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- Which antiemetic is used to inhibit levodopa induced vomiting without blocking its antiparkinsonian effect
- Dicyclomine
- Domperidone
- Itopride
- Ondansetron
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Page 2 of 3
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QP CODE: 1028
Rajiv Gandhi University of Health Sciences, Karnataka
- An Orphan Drug is
- Low cost drug
- Inert drug
- Drug for rare disease/condition
- An essential drug
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This download link is referred from the post: RGUHS MBBS 2nd Year Last 15 Years 2010-2025 Previous Question Papers (Rajiv Gandhi University of Health Sciences)
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