QP CODE : 1026
Rajiv Gandhi University of Health Sciences, Karnataka
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MBBS Phase – II (CBME) Degree Examination - 02-Dec-2024
Time: Three Hours Max. Marks: 100
PATHOLOGY – PAPER I (RS-4)
Q.P. CODE: 1026
(QP contains two pages)
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Your answers should be specific to the questions asked
Draw neat, labeled diagrams wherever necessary
LONG ESSAYS 2 x 10 = 20 Marks
-
A 25 years male, with complains of Bee sting on the face, develop severe pain and swelling within 10 minutes; brought to emergency room in confused state, with difficulty in breathing and abdominal cramps.
a) What is the diagnosis related to this reaction?
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b) Write in detail about the pathogenesis, morphology and evolution of this reaction.
-
A 2 years female child, presented with moderate pallor and jaundice. Clinical history of multiple blood transfusion and peripheral blood smear show microcytic hypochromic anemia. On examination hepato-splenomegaly present
a) What is your diagnosis?
b) Discuss the pathogenesis of this disease with labelled diagram
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c) What relevant investigation is needed to establish the diagnosis?
SHORT ESSAYS 8 x 5 = 40 Marks
- Turner's syndrome
- Difference between Hodgkin's lymphoma and Non Hodgkin's lymphoma
- Leukemoid reaction
- Discuss the vascular events in inflammation
- CSF in Septic meningitis.
- Define Paraneoplastic syndromes with an example for each of the underlying neoplasm causing it
- Hemophilia A
- Microbial oncogenesis
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SHORT ANSWERS 10 x 3 = 30 Marks
- Define metaplasia with examples
- Fate of a thrombus
- Define apoptosis with examples
- Chemotaxis.
- What is FNAC?
- Romanowsky Stains
- Bombay Blood group
- Vitamin C deficiency
- Ghons complex
- Stains to demonstrate amyloid
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Page 1 of 2
QP CODE: 1026
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Rajiv Gandhi University of Health Sciences, Karnataka
Multiple Choice Questions 10 x 1 = 10 Marks
- i) Anticoagulant of choice for coagulation studies is
- Heparin
- EDTA
- Trisodium citrate
- Double oxalate
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- ii) Actin and Myosin proteins are found in
- Microtubules
- Microfilaments
- Intermediate filaments
- Ribosomes
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- iii) Which one of the following cytokines is involved in tissue repair and fibrosis
- Tissue necrosis factor
- Transforming growth factor ß
- Interleukin - 1
- Interferon
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- iv) The characteristic feature of Langerhans cell is the presence of
- Birbeck granules
- Auer rods
- Owl-eye nuclei
- CD15 positive histiocytes
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- v) Sickle cell trait is protective against
- Filaria
- Falciparum Malaria
- Leishmania
- Trypanosmiasis
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- i) NK Cell inhibitory receptors recognize
- Class I MHC molecules
- Class II MHC molecules
- Toll like receptors
- IFN-Y
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- ii) Familial hypercholesterolemia is caused by mutations in the gene encoding the receptor for
- HDL
- VLDL
- LDL
- Chylomicrons
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- iii) Immune Hydrops fetalis is due to
- Parvovirus B19
- Turner syndrome
- Monozygous Twin pregnancies
- Rh incompatibility
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- iv) The cells associated with formation of chloroma is
- Erythroblast
- Immunoblasts
- Myeloblast
- Lymphoblasts
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- v) The subtype of Hodgkin lymphoma that shows lacunar cells and collagen bands is
- Nodular lymphocyte predominant
- Lymphocyte depleted
- Mixed cellularity
- Nodular sclerosis
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Page 2 of 2
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This download link is referred from the post: RGUHS MBBS 2nd Year Last 15 Years 2010-2025 Previous Question Papers (Rajiv Gandhi University of Health Sciences)