Download VNSGU MBBS 2nd Year Pharmacology Syllabus

B)
GENERAL
PHARMACOLOGY:
(N=7
?

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2)
Pharmacokinetics: Absorption, Distribution, Biotransformation, Elimination
(n=3)
Pharmacodynamics: Principles of Drug Action, Mechanisms of drug action,
Receptors (Nature, Types, Theories, Principles, Regulation)

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(n=1)
Application to pharmacotherapeutics: Relevance of Pharmacokinetics and dynamics
in clinical practice, Sequale of repeated administration of drug
(n=2)
Adverse Drug Reactions

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(n=1)
C)
AUTONOMIC
PHARMACOLOGY:
(N=

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8
?
2)
General
Considerations (n=1)

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Adrenergic
agonists
(n=1)
Adrenergic
antagonists

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I: -blockers
(n=1)
Adrenergic
antagonists
II:

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-blockers
(n=1)
Cholinergic
agonists
(n=1)

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Anticholinesterases
(n=1)
Antimuscarinic
drugs
(n=1)

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Skeletal muscle relaxants
(n=1)
A) CARDIOVASCULAR SYSEM INCLUDING DRUGS AFFECTING
COAGULATION AND THOSE ACTING ON KIDNEYS:

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(N=14 ? 2)
General Considerations and Overview of antihypertensive therapy;
Diuretics
(n=2)
Angiotensin

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Converting
Enzyme
(ACE)
inhibitors
(n=1)

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Sympatholytics
&
vasodilators (n=1)
Management of hypertension

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Antianginal:
Nitrates
&
others (n=1)
Calcium

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channel
blockers
(n=1)
Pharmacotherapy of chest pain
Anticoagulants

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&
Coagulants
Thrombolytics
&
Antiplatelet

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Agents
(n=2)

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Drugs for CCF: Digitalis glycosides, Others agents

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(n=2)

Management of CCF

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Antiarrhythmic
Agents (n=1)
Agents used for the management of shock
(n=1)

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Hypolipidaemic
drugs
(n=1)
Role of Nitric oxide and endothelin to be covered in CVS
..........DK

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E) HAEMATINICS AND HAEMATOPOIETIC
FACTORS:
(N=1)
Agents used in therapy of iron deficiency anaemia and megaloblastic anaemia;
Erythropoietin,

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GM-CSF
(n=1)

Management of anaemia

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F) NEUROPSYCHIATRIC PHARMACOLOGY INCLUDING

INFLAMMATON, PAIN & SUBSTANCE ABUSE
(N=15
?

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2)
General
Considerations (n=1)
Sedative-Hypnotics
(n=2)

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Psychopharmacology: Antianxiety; Antipsychotics; Antidepressants
(n=3)
Antiepileptics
(n=2)
Therapy of neurodegenerative disorders:

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Anti-Parkinsonian agents; cerebral vasodilators/nootropics
(n=1)
Local anaesthetics
(n=1)
Analgesics: Opioids; NSAIDs (n=3)

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Pharmacotherapy of pain including migraine
Pharmacotherapy of rheumatoid arthritis and gout

Substance abuse: Management of opioid, alcohol and tobacco addictions
(n=1)

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G)
MISCELLANEOUS
TOPICS
-
I:

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(N=6
?
2)
Autocoids (to be covered before pain lectures)
(n=1)

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Antiallergics:
Antihistaminics (n=1)
Drugs
used
for

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bronchial
asthma
(n=1)
Pharmacotherapy of cough

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Drugs acting on immune system:
Immunostimulants, immunosuppressants; pharmacology of vaccines & sera
(n=1)
Drugs
acting

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on
the
uterus
(n=1)
H) CHEMOTHERAPY INCLUDING CANCER CHEMOTHERAPY:

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(N=22 ? 2)
General
considerations (n=1)
Antimicrobial agents:
(n=7)

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?
Sulphonamides & Cotrimoxazole
?
Quinoline derivatives
?

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Penicillins, Cephalosporins & Other Lactams
?
Aminoglycosides
?
Macrolides

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?
Tetracyclines & Chloramphenicol
Pharmacotherapy of UTI

General

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principles
of
Antimicrobial
use
(n=1)

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Antimycobacterial therapy: Anti-Kochs agents; Anti-leprotic agents
(n=3)
Pharmacotherapy of tuberculosis

Antiprotozoal agents:

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Antiamoebic, Antimalarials and Anti Kala azar
(n=3)

Pharmacotherapy of malaria
Antihelminthics

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(n=1)
(against intestinal Nematodes and Cestodes; extra intestinal Nematodes and Trematodes)
Antifungal
agents
(n=1)

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Antiviral agents including antiretroviral agents
(n=2)
Pharmacotherapy
of
STDs

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(n=1)
Principles of cancer chemotherapy and their adverse drug reactions
(n=1)
(individual agents and regimes need not be taught)

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I) ENDOCRINOLOGY:

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(N=12 ? 2)

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VEER NARMAD SOUTH GUJARAT UNIVERSITY, SURAT.

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S.Y. M.B.B.S.
Introduction to endocrinology
(including Hypothalamic and Anterior Pituitary hormones)
(n=1)
Steroids

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(n=2)

Glucocorticoids: Use and Misuse
Oestrogens
&

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antagonists
(n=1)
Progestins
&
antagonists

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(n=1)
Oral
contraceptives
&
profertility

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agents
(n=1)
Testosterone
&
anabolic

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steroids
(n=1)

Fertility control
Thyroxine

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and
antithyroid
agents
(n=2)
Agents

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affecting
calcification
(n=1)
Antidiabetic agents: Insulin; Oral antidiabetic drugs
(n=2)

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Pharmacotherapy of Diabetes Mellitus

J) AGENTS USED IN GASTROINTESTINAL
DISORDERS:
(N=2)

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Pharmacotherapy
of
nausea
&
vomiting

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(n=1)
Pharmacotherapy
of
peptic
ulcer

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(n=1)

Management of dyspepsia
Management of diarrhoea and constipation

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K) PERIOPERATIVE MANAGEMENT: to be covered as a case study

Preanaesthetic medication
Preparation of surgical site: antiseptics etc.
Local Anaesthetics

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Skeletal muscle relaxants
Drugs used in post-operative period: analgesics, antiemetics etc.
L) MISCELLANEOUS
TOPICS
?

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II
(N=5-7)
Drug-Drug Interactions
(n=1)
Drug use at extremes of age, in pregnancy & in organ dysfunction

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(n=2)
Use of chelating agents in heavy metal poisonings; Environmental & occupational
toxicants and principles of management (particularly cyanide and CO)
(n=1)
Ocular

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pharmacology
(n=1)
Dermatopharmacology (n=1)
General Anaesthetics...DK

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Pharmacotherapy of glaucoma and conjunctivitis

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M)
RATIONAL
PHARMACOTHERAPY: (N=4)

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Prescription writing and P-drug concept
Rational Drug Use; Essential Drug List (EDL)

Criticism with reference to Fixed Drug Combinations (FDCs)
Use and misuse of commonly used preparations: vitamins, antioxidants, enzymes etc.

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d. Term-wise
distribution
I term
Introduction

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General pharmacology
Autonomic pharmacology
Drugs acting on cardiovascular system including drugs affecting coagulation and those acting on the
kidneys
II term

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Prescription writing and P-drug concept
Rational use of drugs; Essential drug list
Neuro-psychiatric pharmacology including inflammation, pain and substance abuse
Miscellaneous topics - I
Chemotherapy

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Endocrinology
III term
Agents used in gastro-intestinal disorders
Peri operative management
Miscellaneous topics

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Criticism with reference to FDCs
Use and misuse of commonly used preparations: vitamins, antioxidants, enzymes etc.

e.
Practicals: Total hours, number & contents

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Total hours: 120
Number:
18
Contents:

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I term practicals

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(N=7)

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Introduction to Practical Pharmacology, Prescription Writing, Pharmacokinetics I, Routes of
Administration: Oral, Routes of Administration: Topical, Routes of Administration:
Parenteral, Pharmacokinetics II: Applied Pharmacokinetics

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II term practicals

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(N=7)
Pharmacodynamics I (Isolated Tissue, Cat NM junction), Pharmacodynamics II (Dog: BP

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and Respiration), Screening Techniques for New Drugs, Adverse Drug Reactions, Rational
Pharmacotherapy I, Rational Pharmacotherapy II, Sources of Drug Information including
scrutiny of Promotional Literature
III
term

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practicals
(N=4)
Case Study 1, Case Study 2
Revision Practicals (n=2)

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f. Books
recommended :

1. Basic & Clinical Pharmacology. Katzung BG (Ed), Publisher: Prentice Hall International
Ltd., London.

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2. Pharmacology & Pharmacotherapeutics. Satoskar RS, Bhandarkar SD (Ed), Publisher:
Popular Prakashan, Bombay.
3. Essentials of Medical Pharmacology. Tripathi KD (Ed), Jaypee Brothers,
publisher:Medical Publishers (P) Ltd.
4. Clinical Pharmacology. Laurence DR, Bennet PN, Brown MJ (Ed). Publisher: Churchill

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Livingstone

Reference books :

2. Goodman & Gilman's The Pharmacological Basis of Therapeutics. Hardman JG &

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Limbird LE (Ed), Publisher: McGraw-Hill, New York.
3. A Textbook of Clinical Pharmacology. Roger HJ, Spector RG, Trounce JR (Ed),
Publisher: Hodder and Stoughton Publishers.

5. Evaluation

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a.
Methods

Theory, Practical & viva

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b. Pattern of Theory Examination including Distribution of Marks,
Questions & Time
Nature of Question Paper
i) Total duration -

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4 hrs (each paper of 2 hrs or 120 minutes)
ii)
Each paper of 3 sections

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