GENERAL
PHARMACOLOGY:
(N=7
?
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2)Pharmacokinetics: Absorption, Distribution, Biotransformation, Elimination
(n=3)
Pharmacodynamics: Principles of Drug Action, Mechanisms of drug action,
Receptors (Nature, Types, Theories, Principles, Regulation)
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(n=1)Application to pharmacotherapeutics: Relevance of Pharmacokinetics and dynamics
in clinical practice, Sequale of repeated administration of drug
(n=2)
Adverse Drug Reactions
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(n=1)C)
AUTONOMIC
PHARMACOLOGY:
(N=
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8?
2)
General
Considerations (n=1)
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Adrenergicagonists
(n=1)
Adrenergic
antagonists
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I: -blockers(n=1)
Adrenergic
antagonists
II:
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-blockers(n=1)
Cholinergic
agonists
(n=1)
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Anticholinesterases(n=1)
Antimuscarinic
drugs
(n=1)
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Skeletal muscle relaxants(n=1)
A) CARDIOVASCULAR SYSEM INCLUDING DRUGS AFFECTING
COAGULATION AND THOSE ACTING ON KIDNEYS:
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(N=14 ? 2)General Considerations and Overview of antihypertensive therapy;
Diuretics
(n=2)
Angiotensin
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ConvertingEnzyme
(ACE)
inhibitors
(n=1)
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Sympatholytics&
vasodilators (n=1)
Management of hypertension
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Antianginal:Nitrates
&
others (n=1)
Calcium
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channelblockers
(n=1)
Pharmacotherapy of chest pain
Anticoagulants
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&Coagulants
Thrombolytics
&
Antiplatelet
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Agents(n=2)
Drugs for CCF: Digitalis glycosides, Others agents
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(n=2)
Management of CCF
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Antiarrhythmic
Agents (n=1)
Agents used for the management of shock
(n=1)
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Hypolipidaemicdrugs
(n=1)
Role of Nitric oxide and endothelin to be covered in CVS
..........DK
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E) HAEMATINICS AND HAEMATOPOIETICFACTORS:
(N=1)
Agents used in therapy of iron deficiency anaemia and megaloblastic anaemia;
Erythropoietin,
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GM-CSF(n=1)
Management of anaemia
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F) NEUROPSYCHIATRIC PHARMACOLOGY INCLUDINGINFLAMMATON, PAIN & SUBSTANCE ABUSE
(N=15
?
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2)General
Considerations (n=1)
Sedative-Hypnotics
(n=2)
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Psychopharmacology: Antianxiety; Antipsychotics; Antidepressants(n=3)
Antiepileptics
(n=2)
Therapy of neurodegenerative disorders:
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Anti-Parkinsonian agents; cerebral vasodilators/nootropics(n=1)
Local anaesthetics
(n=1)
Analgesics: Opioids; NSAIDs (n=3)
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Pharmacotherapy of pain including migrainePharmacotherapy of rheumatoid arthritis and gout
Substance abuse: Management of opioid, alcohol and tobacco addictions
(n=1)
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G)MISCELLANEOUS
TOPICS
-
I:
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(N=6?
2)
Autocoids (to be covered before pain lectures)
(n=1)
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Antiallergics:Antihistaminics (n=1)
Drugs
used
for
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bronchialasthma
(n=1)
Pharmacotherapy of cough
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Drugs acting on immune system:
Immunostimulants, immunosuppressants; pharmacology of vaccines & sera
(n=1)
Drugs
acting
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onthe
uterus
(n=1)
H) CHEMOTHERAPY INCLUDING CANCER CHEMOTHERAPY:
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(N=22 ? 2)General
considerations (n=1)
Antimicrobial agents:
(n=7)
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?Sulphonamides & Cotrimoxazole
?
Quinoline derivatives
?
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Penicillins, Cephalosporins & Other Lactams?
Aminoglycosides
?
Macrolides
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?Tetracyclines & Chloramphenicol
Pharmacotherapy of UTI
General
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principlesof
Antimicrobial
use
(n=1)
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Antimycobacterial therapy: Anti-Kochs agents; Anti-leprotic agents(n=3)
Pharmacotherapy of tuberculosis
Antiprotozoal agents:
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Antiamoebic, Antimalarials and Anti Kala azar(n=3)
Pharmacotherapy of malaria
Antihelminthics
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(n=1)(against intestinal Nematodes and Cestodes; extra intestinal Nematodes and Trematodes)
Antifungal
agents
(n=1)
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Antiviral agents including antiretroviral agents(n=2)
Pharmacotherapy
of
STDs
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(n=1)Principles of cancer chemotherapy and their adverse drug reactions
(n=1)
(individual agents and regimes need not be taught)
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I) ENDOCRINOLOGY:--- Content provided by FirstRanker.com ---
(N=12 ? 2)
VEER NARMAD SOUTH GUJARAT UNIVERSITY, SURAT.
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S.Y. M.B.B.S.Introduction to endocrinology
(including Hypothalamic and Anterior Pituitary hormones)
(n=1)
Steroids
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(n=2)Glucocorticoids: Use and Misuse
Oestrogens
&
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antagonists(n=1)
Progestins
&
antagonists
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(n=1)Oral
contraceptives
&
profertility
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agents(n=1)
Testosterone
&
anabolic
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steroids(n=1)
Fertility control
Thyroxine
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andantithyroid
agents
(n=2)
Agents
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affectingcalcification
(n=1)
Antidiabetic agents: Insulin; Oral antidiabetic drugs
(n=2)
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Pharmacotherapy of Diabetes MellitusJ) AGENTS USED IN GASTROINTESTINAL
DISORDERS:
(N=2)
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Pharmacotherapyof
nausea
&
vomiting
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(n=1)Pharmacotherapy
of
peptic
ulcer
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(n=1)Management of dyspepsia
Management of diarrhoea and constipation
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K) PERIOPERATIVE MANAGEMENT: to be covered as a case studyPreanaesthetic medication
Preparation of surgical site: antiseptics etc.
Local Anaesthetics
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Skeletal muscle relaxantsDrugs used in post-operative period: analgesics, antiemetics etc.
L) MISCELLANEOUS
TOPICS
?
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II(N=5-7)
Drug-Drug Interactions
(n=1)
Drug use at extremes of age, in pregnancy & in organ dysfunction
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(n=2)Use of chelating agents in heavy metal poisonings; Environmental & occupational
toxicants and principles of management (particularly cyanide and CO)
(n=1)
Ocular
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pharmacology(n=1)
Dermatopharmacology (n=1)
General Anaesthetics...DK
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Pharmacotherapy of glaucoma and conjunctivitisM)
RATIONAL
PHARMACOTHERAPY: (N=4)
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Prescription writing and P-drug conceptRational Drug Use; Essential Drug List (EDL)
Criticism with reference to Fixed Drug Combinations (FDCs)
Use and misuse of commonly used preparations: vitamins, antioxidants, enzymes etc.
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d. Term-wise
distribution
I term
Introduction
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General pharmacologyAutonomic pharmacology
Drugs acting on cardiovascular system including drugs affecting coagulation and those acting on the
kidneys
II term
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Prescription writing and P-drug conceptRational use of drugs; Essential drug list
Neuro-psychiatric pharmacology including inflammation, pain and substance abuse
Miscellaneous topics - I
Chemotherapy
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EndocrinologyIII term
Agents used in gastro-intestinal disorders
Peri operative management
Miscellaneous topics
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Criticism with reference to FDCsUse and misuse of commonly used preparations: vitamins, antioxidants, enzymes etc.
e.
Practicals: Total hours, number & contents
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Total hours: 120Number:
18
Contents:
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I term practicals--- Content provided by FirstRanker.com ---
(N=7)
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Introduction to Practical Pharmacology, Prescription Writing, Pharmacokinetics I, Routes ofAdministration: Oral, Routes of Administration: Topical, Routes of Administration:
Parenteral, Pharmacokinetics II: Applied Pharmacokinetics
II term practicals
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(N=7)
Pharmacodynamics I (Isolated Tissue, Cat NM junction), Pharmacodynamics II (Dog: BP
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and Respiration), Screening Techniques for New Drugs, Adverse Drug Reactions, RationalPharmacotherapy I, Rational Pharmacotherapy II, Sources of Drug Information including
scrutiny of Promotional Literature
III
term
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practicals(N=4)
Case Study 1, Case Study 2
Revision Practicals (n=2)
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f. Booksrecommended :
1. Basic & Clinical Pharmacology. Katzung BG (Ed), Publisher: Prentice Hall International
Ltd., London.
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2. Pharmacology & Pharmacotherapeutics. Satoskar RS, Bhandarkar SD (Ed), Publisher:Popular Prakashan, Bombay.
3. Essentials of Medical Pharmacology. Tripathi KD (Ed), Jaypee Brothers,
publisher:Medical Publishers (P) Ltd.
4. Clinical Pharmacology. Laurence DR, Bennet PN, Brown MJ (Ed). Publisher: Churchill
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LivingstoneReference books :
2. Goodman & Gilman's The Pharmacological Basis of Therapeutics. Hardman JG &
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Limbird LE (Ed), Publisher: McGraw-Hill, New York.3. A Textbook of Clinical Pharmacology. Roger HJ, Spector RG, Trounce JR (Ed),
Publisher: Hodder and Stoughton Publishers.
5. Evaluation
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a.
Methods
Theory, Practical & viva
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b. Pattern of Theory Examination including Distribution of Marks,
Questions & Time
Nature of Question Paper
i) Total duration -
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4 hrs (each paper of 2 hrs or 120 minutes)ii)
Each paper of 3 sections