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Download KUHS MBBS Final Year 2025 May 321001 General Medicine Paper I 2019 Scheme Question Paper

Download KUHS (Kerala University of Health Sciences) MBBS (Bachelor of Medicine, Bachelor of Surgery) Final Year 2025 May 321001 General Medicine Paper I 2019 Scheme Previous Question Paper

This post was last modified on 13 September 2025

Q.P. Code: 321001
Reg. no.: .....................
III Professional MBBS Part II Degree Regular/Supplementary Examinations
May 2025
General Medicine Paper I

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(2019 Scheme)
Time: 3 Hours



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Total Marks: 100
Answer all questions to the point neatly and legibly ? Do not leave any blank pages between answers
Indicate the question number correctly for the answer in the margin space
Answer all parts of a single question together ? Leave sufficient space between answers
Draw table/diagrams/flow charts wherever necessary

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1. Multiple Choice Questions
(20x1=20)
The MCQ questions (Q.No. i to Q.No. xx) shall be written in the space provided for answering MCQ
questions at page No. 51 of the answer book (the inner portion of the back cover page (PART III)).
Responses for MCQs marked in any other part/page of the answer book will not be valued

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Question numbers i-v are case scenario-based questions
A 45-year-old female patient comes with a history of cold intolerance, constipation and menorrhagia. on
examination there was midline neck swelling with firm in consistency. The investigations revealed the
following : TSH is 28micrIU/ml,T3 is 0.03ng/dl and T4 is 0.5microgm/dl. The thyroid iodine scan reveals
reduced uptake

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i. What is your likely diagnosis
a) Hypothyroidism
c) Subclinical hypothyroidism
b) Secondary Hyperthyroidism
d) Primary Hyperthyroidism

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ii. What is the most common cause for the above condition
a) Hashimotos Thyroiditis
c) Subacute Thyroiditis
b) De Quervain's Thyroiditis
d) Thyroid Cyst

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iii. What is the main pathophysiology of this condition
a) Diffuse lymphocytic infiltration of the organ
c) Diffuse basophils infiltration
b) Diffuse eosinophilic infiltration
d) Extensive neutrophilic infiltration

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iv. what is the treatment of choice
a) Levothyroxine
b) Carbimazole
c) Corticosteroid
s

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d) ACT
H
v.
The following is NOT a complication of this condition
a) Hypertension

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b) High VLD
L
c) Hair loss
d) Atrial fibrillatio
n

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Questio
n numbers vi-x consist of two statements
- Assertion (A) and Reason (R). Answer these
questions by selecting the appropriate options given belo
w

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vi. Assertio
n (A): The loose stools lastin
g for more than 4 weeks is chroni
c diarrhe
a

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Reaso
n (R): The most common cause is noninfectious in origin, due to GIT secretary abnormalit
y
a) Both A and R are true and R is the correct explanation of
A

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c) A is true but R is fal
se
b) Both A and R are true but R is not the correct explanation of A
d) A is false but R is tru
e

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vii. Assertion (A): The passing more than 3litra/day of urine is called as polyuria
Reason(R): Polyuria is due to defect in aquaporin receptors and excretion of non absorbable solutes
through kidney
.
a) Both A and R are true and R is the correct explanation of

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A
c) A is true but R is fal
se
b) Both A and R are true but R is not the correct explanation of A d) A is false but R is tru
e

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viii. Assertion (A): B12 deficiency is the most common reason for Megaloblastic anaemia
Reason(R): B12 deficiency is the reason for Hyper segmente
d Neutrophil
s
a) Both A and R are true and R is the correct explanation of

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A
c) A is true but R is fal
se
b) Both A and R are true but R is not the correct explanation of A d) A is false but R is tru
e

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ix. Assertion (A): Sulfonyl ureas are oral hypoglycemic agent
s
Reason(R): Sulfonyl urea
s increases the insulin secretion
a) Both A and R are true and R is the correct explanation of

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A
c) A is true but R is fal
se
b) Both A and R are true but R is not the correct explanation of A d) A is false but R is tru
e

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x. Assertion (A):
The rise in temperature of more than 37.7oC is called as fever
Reason(R): The resetting of hypothalamic set point is the reason for hyperthermia
a) Both A and R are true and R is the correct explanation of A
c) A is true but R is false

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b) Both A and R are true but R is not the correct explanation of A d) A is false but R is true




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(PTO)




Question numbers xi-x

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v are multiple response type questions. Read the statements and mark the
most appropriate answer
xi. Most common cause
s of collapsing pulse ar
e

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1) Aortic regurgitatio
n
2) Mitral regurgitation 3) Peripheral AV fistul
a
4) Ventricular seftal defect

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a) 1 & 2 are correc
t
b) 1 & 3 are corre
ct
c) 3

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& 4 are correc
t
d) 2 & 4 are correc
t
xii. Most common causes of Acute bacterial meningitis are

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1) Streptococcus pneumonia
2) Neisseria meningitide
s
3) E coli
4) Proteus

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a) 1 & 2 are correc
t
b) 1 & 3 are correc
t
c) 3 & 4 are correc

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t
d) 2 & 4 are correct
xiii. Follow up drugs used in acute ischemic stroke to prevent the recurrence of stroke in future ar
e
1) Aspirin

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2) Naproxe
n
3) Statins
4) Corticosteroid
s

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a) 1 & 2 are correc
t
b) 1 & 3 are correc
t
c) 3 & 4 are correc

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t
d) 2 & 4 are corre
ct
xiv. The thrombolysis is done in
1) Acute STEM

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I
2) Acute ischemic stroke of <4.5 hours 3) Acute NSTEM
I
4) Unstable angin
a

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a) 1 & 2 are correc
t
b) 1 & 3 are correc
t
c) 3 & 4 are correc

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t
d) 2 & 4 are corre
ct
xv. The drugs used to treat hyperkalemia ar
e

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1) Sodium bicarbonat
e
2) Short acting Insulin with glucose 3) Magnesiu
m
4) Sevelamer

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a) 1 & 2 are correc
t
b) 1 & 3 are correc
t
c) 3 & 4 are correc

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t
d) 2 & 4 are corre
ct
Questio
n numbers xvi-xx are single response type questions

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xvi. The following are Metabolic Syndrome components, EXCEP
T
a) FBS >100 mg/d
l
c) Triglycerides >150 mg/dl

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b) BP >130/80mmh
g
d) LDL cholesterol>150mg/d
l
xvii. The following are features of Addison's disease, EXCEP

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T
a) Astheni
a
b) Hyperkalemi
a

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c) Hypoglycemia
d) Hypocalcemi
a
xviii. The following are criteria of diagnosi
s of Type 2 Diabetes mellitus, EXCEP

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T
a) HbA1c>6.5
%
c) PPBS >200 mg/d
l

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b) FBS >126 mg/dl
d) PPBS >180 mg/d
l
xix. The following drugs have proven to be having mortality benefits in Congestive heart failure, EXCEP
T

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a) ACE inhibitors
c) Aldosterone antagonist
s
b) Beta blockers
d) Digoxi

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n
xx.
The following are ECG features of hyperkalemia, EXCEPT
a) Tall T waves
c) Sinewaves patter

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n
b) Absence of p waves
d) Long QT interval
Long Essays:
(2x10=20)

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2. Discuss about the etiopathology, clinical feature
s, investigations, treatment and complications of acute
coronary syndrom
e
(2+2+2+2+2

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)
3.
A 50 years old male who is a chronic alcoholic and smoker, on irregular medications for
diabetes was brought to the casualty at 8.30 am with history of sudden onset unresponsiveness since
morning 7.00 am. On examination patient is drowsy with facial deviation to left side, paucity of

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movement of right side body, with exaggerated deep tendon reflexes and extensor plantar on the same
side: BP: 170/120 mm/Hg
a) What is your anatomical and etiological diagnosis
b) What are the modifiable and nonmodifiable risk factors
c) What are the relevant investigations to be done

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d) How do you manage the above patient

e) Define TIA and explain the significance of TIA in the above case scenario. "

(1+2+2+3+2)

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S
hort E ssays:
(6x6=36)
4. Hypoglycemi
a

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5. CML
6. Arterial Pulse
7. Irrit
able bowel syndrome
8. Hyponatremia

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9. AKI
Sh

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ort Answers:
(6x4=24)
10. Hepatitis B infecti
on
11. Role of physician in socie

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ty
12. Status Epilepticus
13. Eisenmenger's syndrom
e
14. Acute Metabolic Acidosis

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15. Acute Pulmonary edema
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