KAIJI NARAYANA RAO UNIVERSITY OF HEALTH SCIENCES
WARANGAL, TELANGANA STATE ? 506 002
MBBS SECOND YEAR DEGREE EXAMINATIONS: AUGUST 2025
MICROBIOLOGY PAPER-I
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Time: 3 Hours Max Marks: 100Note: Answer all questions Give Diagrammatic representation where ever
necessary
Multiple Choice Questions: 10 X 1 = 10
1. Endoscopes are sterilized using which of the following methods?
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a) Glutaraldehydeb) Formaldehyde
c) Autoclaving
d) Hot air oven
2. Which of the following is a primary lymphoid organ?
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a) Spleenb) Mucosa associated Lymphoid Tissue
c) Thymus
d) Tonsils
3. African sleeping sickness is caused by
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a) Leishmania donovanib) Trypanosoma brucei
c) Trypanosoma cruzei
d) Trypanosoma rangei
4. Which is more antigenic in inducing immune response
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a) Nucleic acidb) Carbohydrate
c) Protein
d) Lipid
5. Which of the following hepatitis viruses is not transmitted parenterally?
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a) Hepatitis B virusb) Hepatitis D virus
c) Hepatitis C virus
d) Hepatitis E virus
6. The most common mode of transmission of Brucella is
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a) Direct contactb) Air borne
c) Man to man
d) Ingestion of raw milk
7. Which one of the following methods of antimicrobial susceptibility
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testing does not detect MIC (minimum inhibitory concentration)?a) Disk Diffusion test
b) Broth Dilution method
c) Agar Dilution method
d) Epsilometer test
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8. Rate of infection occurring at a higher rate than usual in a particulargeographical area is known as
a) Epidemic
b) Pandemic
c) Hyper endemic
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d) Sporadic
9. Prozone phenomenon in Ag Ab reaction is due to
a) Excess antibodies
b) Excess antigen
c) Hyperimmune serum
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d) Complement excess10. Which of the following is not a potentially highly infectious specimen for
occupational injury in health care settings
a) Blood
b) CSF
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c) Salivad) Semen
Essay/ Long Answer Questions: 2 X 15 = 30
11. Enumerate the properties and types of Antigen- Antibody Reaction.
Describe in detail about the principle, types and applications of ELISA.
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(6+2+4+3)12. Discuss in detail the laboratory diagnosis of Viral Infections. (15)
Short Answer Questions: 7 X 6 = 42
13. Amoebic Liver Abscess.
14. Mechanism of Antibiotic Resistance.
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15. Stool concentration techniques.16. Graft versus Host Reaction.
17. Post exposure Prophylaxis for HIV.
18. Q Fever.
19. Kyasanur Forest Disease.
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Very Short Answer Questions: 6 X 3 = 18
20. Adjuvants.
21. Dimorphic Fungi.
22. Germ Tube.
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23. Name three Tumour associated Antigens.24. Classification of Arbo Viruses.
25. Name three diseases caused by Superantigens.
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