KAIJI NARAYANA RAO UNIVERSITY OF HEALTH SCIENCES
WARANGAL, TELANGANA STATE ? 506 002
MBBS SECOND YEAR DEGREE EXAMINATIONS: AUGUST 2025
MICROBIOLOGY PAPER-II
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Time: 3 Hours Max Marks: 100Note: Answer all questions Give Diagrammatic representation where ever
necessary
Multiple Choice Questions: 10 X 1 = 10
1. Which of the following is not considered a potential agent of
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bioterrorism and biologic warfare?a) Yersinia pestis
b) Botulinum toxin
c) Streptococcus pyogenes
d) Bacillus anthracis
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2. In a patient with bubonic form of plague, all the following specimens areacceptable for diagnosis except
a) Stool culture
b) Blood culture
c) Culture of lymph node aspirate
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d) Acute and convalescent serum3. Staphylococcus epidermidis may cause:
a) Toxic shock syndrome
b) Stitch abscess
c) Staphylococcal scalded skin syndrome
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d) All of the above
4. Soft chancre is caused by
a) Treponema pallidum
b) Neisseria gonorrhoeae
c) Haemophilus ducreyi
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d) Chlamydia trachomatis5. Tissue should be segregated in which colour bag?
a) Yellow
b) Blue
c) Red
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d) Black6. Subacute sclerosing panencephalitis is a complication of
a) Mumps
b) Measles
c) Rubella
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d) Rabies7. Which of the following is not used as an indicator organism of faecal
contamination of water
a) Escherichia coli
b) Salmonella typhi
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c) Faecal Streptococcid) Pseudomonas
8. Intracellular survival of Mycobacterium tubercle bacilli inside the
macrophage is due to
a) Inhibition of entry into host cell
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b) Inhibition of entry into phagosomec) Inhibition of phagosome and lysosome fusion
d) Inhibition of degradation by lysosomal enzymes
9. Cutaneous leishmaniasis is also called as
a) Delhi boil
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b) Aleppo boilc) Baghdad button
d) All of the above
10. Gene targets for confirmation of COVID 19 includes
a) Spike Protein
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b) Envelope proteinc) Membrane protein
d) RNA dependent RNA polymerase
Essay/ Long Answer Questions: 2 X 15 = 30
11. A 55-year-old male came to OPD with complaints of fever, vomiting,
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severe headache and photophobia since 2 days. On examination he hada temperature of 39? C pulse rate of 96 bpm. He has recently had ear
infection. Neck stiffness was noted. Relevant sample was spent for
confirmation of the diagnosis.
a. Elaborate on the sample collection.
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b. Gram stain report of the sample revealed lens shaped Gram-positiveDiplococci with a halo around and plenty of the Polymorphonuclear cells.
Identify the probable pathogen.
c. Elaborate on laboratory tests done to confirm the pathogen.
d. Add a note on Prophylaxis and treatment available for this pathogen.
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(3+2+5+5)12. A farmer presented to the OPD with history of Papulo Vesicular Lesion
over the neck. Which later on developed into a coal black, necrotic
wound for the past 3 days, tissue from the necrotic area on Gram
staining revealed Gram positive bacilli arranged in chains.
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a. What is the clinical diagnosis and causative agent?b. Describe the pathogenesis and various forms of clinical presentation of this
infection
c. Describe the laboratory investigations to confirm the diagnosis. (2+6+7)
Short Answer Questions: 7 X 6 = 42
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13. Guinea worm infection.14. Gonorrhoea- pathogenesis and Lab diagnosis
15. Laboratory diagnosis of Diphtheria.
16. Mumps.
17. Extra intestinal amoebiasis.
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18. Mucormycosis.19. Lab diagnosis of Extra Pulmonary Tuberculosis.
Very Short Answer Questions: 6 X 3 = 18
20. Name three Zoonotic Diseases.
21. What is the color coding for Biomedical Waste according to BMW
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management rules 2016.22. Congenital Syphilis.
23. DPT Vaccine.
24. Name three Microfilaria of medical importance.
25. Name three agents causing Ocular Mycoses.
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