Download KNRUHS MBBS 2nd Year Pathology Paper I 2025 June Question Paper

KALOJI NARAYANA RAO UNIVERSITY OF HEALTH SCIENCES, WARANGAL,
TELANGANA-506 002
MBBS SECOND YEAR DEGREE EXAMINATIONS: JUNE, 2025 - PATHOLOGY
Paper -I
Time: 3 Hours Max Marks: 100

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Note: Answer all questions. Give Diagrammatic representation wherever
necessary.
Multiple Choice Questions: (10 x 1 = 10)
1. Epstein Barr virus causes all EXCEPT:
a) Infectious Mononucleosis

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b) Nasopharyngeal carcinoma
c) Burkitt's lymphoma
d) Acute myeloid leukaemia
2. Interstitial pulmonary fibrosis can occur due to all except:
a) Busulfan

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b) Nitrofurantoin
c) Tetracycline
d) Bleomycin
3. All of the following is true for anaemia of chronic diseases except?
a) Low serum iron levels

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b) Low erythropoietin
c) Increased hepcidin
d) Low ferritin
4. Defect in sickle cell disease is

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a) Glutamate residue instead of a valine residue at the 6th amino acid position

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in (3-globin
b) Valine residue instead of a glutamate residue at the 6th amino acid position
in 13-globin
c) Glutamate residue instead of a valine residue at the 6th amino acid position
in a -globin

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d) Valine residue instead of a glutamate residue at the 6th amino acid position
in a-globin
5. Hodgkin lymphoma with frequent mononuclear cells and classical Reed
Sternberg
a) Nodular sclerosis

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b) Lymphocyte depletion
c) Mixed cellularity
d) Lymphocyte predominance
6. Idiopathic thrombocytopenic purpura is characterized by:
a) Decreased platelet survival

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b) Decreased production of platelets
c) Hypersplenism
d) Dilutional thrombocytopenia
7. Bombay phenotype are the individuals who:
a) Lack H genes and therefore H substance

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b) Possess A, B antigens
c) Secrete excessive amount of H substance
d) Lack C, D and E antigens
8. Cyclin dependent Kinases are all except
a) P57

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b) P21
c) P53
d) P27
9. Not a stain for Amyloid is
a) Congo red

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b) Methyl violet
c) Triphenyl tetrazolium chloride
d) Thioflavin T
10. Not a cause of oedema is
a) Increased hydrostatic pressure

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b) Increased plasma oncotic pressure
c) Lymphatic obstruction
d) Sodium retention
Essay/ Long Answer Questions: (2 x 15 = 30)
11. Define Apoptosis. Describe morphological features and mechanism of

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Apoptosis. (2+6+7)
12. Define and Classify of Leukaemia. Discuss the Chromosomal abnormality
and lab findings in Chronic Myeloid Leukaemia. (2+3+4+6)
Short Answer Questions: (7 x 6 = 42)
13. Discuss about pathological Calcification.

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14. Describe Gaucher's Disease.
15. Von Willebrand's Disease.
16. Transplant rejection.
17. Factors affecting Wound Healing.

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18. Pathology of Vitamin D deficiency.

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19. Aplastic Anaemia.
Very Short Answer Questions: (6 x 3 = 18)
20. Three types of Necrosis with examples.
21. CSF findings in Pyogenic Meningitis.
22. Three Opportunistic infections in HIV infection.

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23. Morphology of Megaloblast.
24. Enumerate anticoagulants in Haematology.
25. Indications of Semen Analysis.
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