Download PTU M.Pharma 2020 Dec 1st Sem 74657 Modern Pharmaceutical Analytical Techniques Question Paper

Roll No.

Total No. of Pages : 02

Total No. of Questions : 08

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M.Pharmacy (Pharmaceutics) (2017 & Onwards) (Sem.-1)

MODERN PHARMACEUTICAL ANALYTICAL TECHNIQUES

Subject Code : MPH-101T

M.Code: 74657

Time: 2 Hrs.

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Max. Marks : 37.5

INSTRUCTIONS TO CANDIDATES :

1. Attempt any FIVE question(s), each question carries 7.5 marks.

1. 1. Explain the theory of Fluorescence.
   2. Give the labelled diagram for FTIR spectrophotometer.

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2. 1. What is the principle of atomic absorption spectroscopy?
   2. Briefly explain following in NMR: Deuterium exchange, chemical shift and spine spin coupling
3. 1. Give comparative statements on various analyzers used in Mass spectrometry.

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   2. Briefly explain following in Mass spectrometry: Isotope peaks, Chemical ionization
4. 1. What is the principle of affinity chromatography?
   2. Describe the factors affecting resolution in column chromatography.

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5. 1. What is the basic principle of electrophoresis?
   2. What is zone electrophoresis?
6. Explain the basic principle of Radio immune assay (RIA). Describe various type of RIAs used in the estimation of enzyme activity and drug in biological fluids.
7. 1. Discuss the effect of solvent polarity on Amax of n ?* excitation.

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   2. Explain the principle of FT-NMR.
8. 1. Describe the specific applications of ion exchange chromatography.
   2. Briefly describe generation of X-rays in X-ray crystallography.

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