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Download MBBS 1st Year 527056 Biochemistry Paper II Aug 2025 mcq Question Paper

Download MBBS (Bachelor of Medicine and Bachelor of Surgery) 1st Year 527056 Biochemistry Paper II Aug 2025 mcq Previous Question Paper

This post was last modified on 14 September 2025

D
r. . MEDICAL

[MBBS 0825] AUGUST 2025 Sub. Code: 7056

--- Content provided by‍ FirstRanker.com ---

M.B.B.S. DEGREE EXAMINATION
(For the candidates admitted from the Academic Year 2024-2025)

FIRST PROFESSIONAL ? (CBME)
PAPER II ? BIOCHEMISTRY

--- Content provided by‍ FirstRanker.com ---

Q.P. Code: 527056
Time: 20 Minutes Maximum : 20 Marks
Answer All Questions
Shade the correct answer with Black or Blue ink ball point pen
SET - A

--- Content provided by⁠ FirstRanker.com ---


IV. Multiple Choice Questions:


(20 x 1 = 20)

--- Content provided by‌ FirstRanker.com ---


1. Which of the following is hydroxyl aminoacid
A) Threonine B) Histidine C) Leucine D) Isoleucine
2. All of the following reagents are used in sequencing of proteins EXCEPT
A) Dansyl chloride B) Phenylhydrazine

--- Content provided by‌ FirstRanker.com ---

C) Phenylisothiocyanate D) Cyanogen bromide
3. Recombinant Human Insulin differ from bovine Insulin by
A) Biological activity B) Aminoacid sequence
C) Position of disulfide bonds D) Side chains
4. A 45 year old software engineer vegetarian by diet goes for master health checkup,

--- Content provided by‌ FirstRanker.com ---

report shows elevated homocysteine levels. Hyperhomocysteinemia can occur in all
the following Vitamin deficiency EXCEPT
A) Pyridoxine B) Cyanocobalamin C) Pantothenic acid D) Folic acid
5. All are true about Lysine EXCEPT
A) An essential aminoacid B) Ketogenic

--- Content provided by​ FirstRanker.com ---

C) Deficient in Cereals D) Deficient in Pulses
6. All of the following metabolic disorders are associated with mental retardation EXCEPT
A) Phenylketonuria B) Von Gierke's Disease
C) Maple syrup urine disease D) Morteaux Lamy Syndrome
7. An adult male in 4th decade presented with severe low back ache. Oochronosis is seen in

--- Content provided by FirstRanker.com ---

A) Tyrosinemia B) Carcinoid syndrome C) Albinism D) Alkaptonuria
8. Gastric acid secretion is stimulated by all EXCEPT
A) Gastrin B) Pepsin C) Vagal stimulation D) Histamine
9. Proteinuria is not a feature in
A) Diabetes insipidus B) Multiple myeloma

--- Content provided by​ FirstRanker.com ---

C) Acute Glomerulonephritis D) Nephrotic syndrome
... 2 ...

... 2 ...
10. Renal stones may contain any of the following constituents EXCEPT
A) Uric acid B) Calcium C) Cholesterol D) Cystine

--- Content provided by‍ FirstRanker.com ---

11. A 50 year old male presented with Chronic Renal Failure and investigated for the
same. Which ion in serum is decreased in Chronic Renal Failure?
A) Potassium B) Phosphate C) Hydrogen D) Bicarbonate
12. Haptoglobin is a carrier of
A) Free iron B) Free heme C) Free hemoglobin D) Free bilirubin

--- Content provided by FirstRanker.com ---

13. Albumin is a transporter of the following compounds in plasma EXCEPT
A) Non esterified fatty acids B) Bilirubin C) Calcium D) Iron
14. Pick out the mismatched pair
A) Albumin and bilirubin B) Hemopexin and heme
C) Transthyretin and Thyroxine D) Transcortin and estrogen

--- Content provided by⁠ FirstRanker.com ---

15. Which of the following enzyme is involved in Phase II detoxification?
A) Cytochrome p450 B) N acetyl transferase
C) UDP glucronyl transferase D) Alcohol dehydrogenase
16. A 65 year old male present with features of hyperuricemia secondary to a systemic
disease. Secondary hyperuricemia is seen in all the following conditions EXCEPT

--- Content provided by‍ FirstRanker.com ---

A) Leukemia B) Psoriasis C) Cytotoxic therapy D) Hepatitis
17. Which enzyme protects DNA from aging?
A) DNA polymerase B) Topoisomerase
C) Deoxyribonuclease D) Telomerase
18. Denaturation of DNA is accompanied by all changes EXCEPT

--- Content provided by FirstRanker.com ---

A) Increase in viscosity B) Hyperchromicity
C) Unstacking of bases D) Destabilisation of DNA helix
19. A baby born to a carrier mother exhibits symptoms of the disease. All of the
following are inherited through X chromosome, EXCEPT
A) Sickle cell anaemia

--- Content provided by​ FirstRanker.com ---

B) Hemophilia
C) Glucose -6-Phosphate dehydrogenase deficiency
D) Duchenne type muscular dystrophy
20. When GAC is replaced by GAA, the result is
A) Silent mutation B) Deletion mutation

--- Content provided by​ FirstRanker.com ---

C) Frameshift mutation D) Conservative mutation
*********
[MBBS 0825]

D
r. . MEDICAL

--- Content provided by‌ FirstRanker.com ---


[MBBS 0825] AUGUST 2025 Sub. Code: 7056

M.B.B.S. DEGREE EXAMINATION
(For the candidates admitted from the Academic Year 2024-2025)

--- Content provided by‌ FirstRanker.com ---


FIRST PROFESSIONAL ? (CBME)
PAPER II ? BIOCHEMISTRY
Q.P. Code: 527056
Time: 20 Minutes Maximum : 20 Marks

--- Content provided by FirstRanker.com ---

Answer All Questions
Shade the correct answer with Black or Blue ink ball point pen
SET - B

IV. Multiple Choice Questions:

--- Content provided by‌ FirstRanker.com ---



(20 x 1 = 20)

1. Recombinant Human Insulin differ from bovine Insulin by

--- Content provided by‍ FirstRanker.com ---

A) Biological activity B) Aminoacid sequence
C) Position of disulfide bonds D) Side chains
2. A 45 year old software engineer vegetarian by diet goes for master health checkup,
report shows elevated homocysteine levels. Hyperhomocysteinemia can occur in all
the following Vitamin deficiency EXCEPT

--- Content provided by‍ FirstRanker.com ---

A) Pyridoxine B) Cyanocobalamin C) Pantothenic acid D) Folic acid
3. All are true about Lysine EXCEPT
A) An essential aminoacid B) Ketogenic
C) Deficient in Cereals D) Deficient in Pulses
4. All of the following metabolic disorders are associated with mental retardation EXCEPT

--- Content provided by⁠ FirstRanker.com ---

A) Phenylketonuria B) Von Gierke's Disease
C) Maple syrup urine disease D) Morteaux Lamy Syndrome
5. An adult male in 4th decade presented with severe low back ache. Oochronosis is seen in
A) Tyrosinemia B) Carcinoid syndrome C) Albinism D) Alkaptonuria
6. Gastric acid secretion is stimulated by all EXCEPT

--- Content provided by‌ FirstRanker.com ---

A) Gastrin B) Pepsin C) Vagal stimulation D) Histamine
7. Proteinuria is not a feature in
A) Diabetes insipidus B) Multiple myeloma
C) Acute Glomerulonephritis D) Nephrotic syndrome
8. Renal stones may contain any of the following constituents EXCEPT

--- Content provided by​ FirstRanker.com ---

A) Uric acid B) Calcium C) Cholesterol D) Cystine
9. A 50 year old male presented with Chronic Renal Failure and investigated for the
same. Which ion in serum is decreased in Chronic Renal Failure?
A) Potassium B) Phosphate C) Hydrogen D) Bicarbonate
... 2 ...

--- Content provided by⁠ FirstRanker.com ---


... 2 ...
10. Haptoglobin is a carrier of
A) Free iron B) Free heme C) Free hemoglobin D) Free bilirubin
11. Albumin is a transporter of the following compounds in plasma EXCEPT
A) Non esterified fatty acids B) Bilirubin C) Calcium D) Iron

--- Content provided by‍ FirstRanker.com ---

12. Pick out the mismatched pair
A) Albumin and bilirubin B) Hemopexin and heme
C) Transthyretin and Thyroxine D) Transcortin and estrogen
13. Which of the following enzyme is involved in Phase II detoxification?
A) Cytochrome p450 B) N acetyl transferase

--- Content provided by⁠ FirstRanker.com ---

C) UDP glucronyl transferase D) Alcohol dehydrogenase
14. A 65 year old male present with features of hyperuricemia secondary to a systemic
disease. Secondary hyperuricemia is seen in all the following conditions EXCEPT
A) Leukemia B) Psoriasis C) Cytotoxic therapy D) Hepatitis
15. Which enzyme protects DNA from aging?

--- Content provided by FirstRanker.com ---

A) DNA polymerase B) Topoisomerase
C) Deoxyribonuclease D) Telomerase
16. Denaturation of DNA is accompanied by all changes EXCEPT
A) Increase in viscosity B) Hyperchromicity
C) Unstacking of bases D) Destabilisation of DNA helix

--- Content provided by⁠ FirstRanker.com ---

17. A baby born to a carrier mother exhibits symptoms of the disease. All of the
following are inherited through X chromosome, EXCEPT
A) Sickle cell anaemia
B) Hemophilia
C) Glucose -6-Phosphate dehydrogenase deficiency

--- Content provided by⁠ FirstRanker.com ---

D) Duchenne type muscular dystrophy
18. When GAC is replaced by GAA, the result is
A) Silent mutation B) Deletion mutation
C) Frameshift mutation D) Conservative mutation
19. Which of the following is hydroxyl aminoacid

--- Content provided by⁠ FirstRanker.com ---

A) Threonine B) Histidine C) Leucine D) Isoleucine
20. All of the following reagents are used in sequencing of proteins EXCEPT
A) Dansyl chloride B) Phenylhydrazine
C) Phenylisothiocyanate D) Cyanogen bromide
*********

--- Content provided by FirstRanker.com ---

[MBBS 0825]

D
r. . MEDICAL

[MBBS 0825] AUGUST 2025 Sub. Code: 7056

--- Content provided by⁠ FirstRanker.com ---


M.B.B.S. DEGREE EXAMINATION
(For the candidates admitted from the Academic Year 2024-2025)

FIRST PROFESSIONAL ? (CBME)

--- Content provided by‌ FirstRanker.com ---

PAPER II ? BIOCHEMISTRY
Q.P. Code: 527056
Time: 20 Minutes Maximum : 20 Marks
Answer All Questions
Shade the correct answer with Black or Blue ink ball point pen

--- Content provided by‍ FirstRanker.com ---

SET - C

IV. Multiple Choice Questions:


--- Content provided by‍ FirstRanker.com ---

(20 x 1 = 20)

1. All of the following metabolic disorders are associated with mental retardation EXCEPT
A) Phenylketonuria B) Von Gierke's Disease
C) Maple syrup urine disease D) Morteaux Lamy Syndrome

--- Content provided by‌ FirstRanker.com ---

2. An adult male in 4th decade presented with severe low back ache. Oochronosis is seen in
A) Tyrosinemia B) Carcinoid syndrome C) Albinism D) Alkaptonuria
3. Gastric acid secretion is stimulated by all EXCEPT
A) Gastrin B) Pepsin C) Vagal stimulation D) Histamine
4. Proteinuria is not a feature in

--- Content provided by​ FirstRanker.com ---

A) Diabetes insipidus B) Multiple myeloma
C) Acute Glomerulonephritis D) Nephrotic syndrome
5. Renal stones may contain any of the following constituents EXCEPT
A) Uric acid B) Calcium C) Cholesterol D) Cystine
6. A 50 year old male presented with Chronic Renal Failure and investigated for the

--- Content provided by FirstRanker.com ---

same. Which ion in serum is decreased in Chronic Renal Failure?
A) Potassium B) Phosphate C) Hydrogen D) Bicarbonate
7. Haptoglobin is a carrier of
A) Free iron B) Free heme C) Free hemoglobin D) Free bilirubin
8. Albumin is a transporter of the following compounds in plasma EXCEPT

--- Content provided by‍ FirstRanker.com ---

A) Non esterified fatty acids B) Bilirubin C) Calcium D) Iron
9. Pick out the mismatched pair
A) Albumin and bilirubin B) Hemopexin and heme
C) Transthyretin and Thyroxine D) Transcortin and estrogen
10. Which of the following enzyme is involved in Phase II detoxification?

--- Content provided by⁠ FirstRanker.com ---

A) Cytochrome p450 B) N acetyl transferase
C) UDP glucronyl transferase D) Alcohol dehydrogenase
... 2 ...

... 2 ...
11. A 65 year old male present with features of hyperuricemia secondary to a systemic

--- Content provided by‍ FirstRanker.com ---

disease. Secondary hyperuricemia is seen in all the following conditions EXCEPT
A) Leukemia B) Psoriasis C) Cytotoxic therapy D) Hepatitis
12. Which enzyme protects DNA from aging?
A) DNA polymerase B) Topoisomerase
C) Deoxyribonuclease D) Telomerase

--- Content provided by FirstRanker.com ---

13. Denaturation of DNA is accompanied by all changes EXCEPT
A) Increase in viscosity B) Hyperchromicity
C) Unstacking of bases D) Destabilisation of DNA helix
14. A baby born to a carrier mother exhibits symptoms of the disease. All of the
following are inherited through X chromosome, EXCEPT

--- Content provided by​ FirstRanker.com ---

A) Sickle cell anaemia
B) Hemophilia
C) Glucose -6-Phosphate dehydrogenase deficiency
D) Duchenne type muscular dystrophy
15. When GAC is replaced by GAA, the result is

--- Content provided by FirstRanker.com ---

A) Silent mutation B) Deletion mutation
C) Frameshift mutation D) Conservative mutation
16. Which of the following is hydroxyl aminoacid
A) Threonine B) Histidine C) Leucine D) Isoleucine
17. All of the following reagents are used in sequencing of proteins EXCEPT

--- Content provided by⁠ FirstRanker.com ---

A) Dansyl chloride B) Phenylhydrazine
C) Phenylisothiocyanate D) Cyanogen bromide
18. Recombinant Human Insulin differ from bovine Insulin by
A) Biological activity B) Aminoacid sequence
C) Position of disulfide bonds D) Side chains

--- Content provided by‍ FirstRanker.com ---

19. A 45 year old software engineer vegetarian by diet goes for master health checkup,
report shows elevated homocysteine levels. Hyperhomocysteinemia can occur in all
the following Vitamin deficiency EXCEPT
A) Pyridoxine B) Cyanocobalamin C) Pantothenic acid D) Folic acid
20. All are true about Lysine EXCEPT

--- Content provided by FirstRanker.com ---

A) An essential aminoacid B) Ketogenic
C) Deficient in Cereals D) Deficient in Pulses
*********
[MBBS 0825]

D

--- Content provided by‌ FirstRanker.com ---

r. . MEDICAL

[MBBS 0825] AUGUST 2025 Sub. Code: 7056

M.B.B.S. DEGREE EXAMINATION

--- Content provided by FirstRanker.com ---

(For the candidates admitted from the Academic Year 2024-2025)

FIRST PROFESSIONAL ? (CBME)
PAPER II ? BIOCHEMISTRY
Q.P. Code: 527056

--- Content provided by‌ FirstRanker.com ---

Time: 20 Minutes Maximum : 20 Marks
Answer All Questions
Shade the correct answer with Black or Blue ink ball point pen
SET - D

--- Content provided by​ FirstRanker.com ---

IV. Multiple Choice Questions:


(20 x 1 = 20)

--- Content provided by⁠ FirstRanker.com ---

1. Haptoglobin is a carrier of
A) Free iron B) Free heme C) Free hemoglobin D) Free bilirubin
2. Albumin is a transporter of the following compounds in plasma EXCEPT
A) Non esterified fatty acids B) Bilirubin C) Calcium D) Iron
3. Pick out the mismatched pair

--- Content provided by FirstRanker.com ---

A) Albumin and bilirubin B) Hemopexin and heme
C) Transthyretin and Thyroxine D) Transcortin and estrogen
4. Which of the following enzyme is involved in Phase II detoxification?
A) Cytochrome p450 B) N acetyl transferase
C) UDP glucronyl transferase D) Alcohol dehydrogenase

--- Content provided by‌ FirstRanker.com ---

5. A 65 year old male present with features of hyperuricemia secondary to a systemic
disease. Secondary hyperuricemia is seen in all the following conditions EXCEPT
A) Leukemia B) Psoriasis C) Cytotoxic therapy D) Hepatitis
6. Which enzyme protects DNA from aging?
A) DNA polymerase B) Topoisomerase

--- Content provided by‌ FirstRanker.com ---

C) Deoxyribonuclease D) Telomerase
7. Denaturation of DNA is accompanied by all changes EXCEPT
A) Increase in viscosity B) Hyperchromicity
C) Unstacking of bases D) Destabilisation of DNA helix
8. A baby born to a carrier mother exhibits symptoms of the disease. All of the

--- Content provided by⁠ FirstRanker.com ---

following are inherited through X chromosome, EXCEPT
A) Sickle cell anaemia
B) Hemophilia
C) Glucose -6-Phosphate dehydrogenase deficiency
D) Duchenne type muscular dystrophy

--- Content provided by‌ FirstRanker.com ---

... 2 ...

... 2 ...
9. When GAC is replaced by GAA, the result is
A) Silent mutation B) Deletion mutation
C) Frameshift mutation D) Conservative mutation

--- Content provided by⁠ FirstRanker.com ---

10. Which of the following is hydroxyl aminoacid
A) Threonine B) Histidine C) Leucine D) Isoleucine
11. All of the following reagents are used in sequencing of proteins EXCEPT
A) Dansyl chloride B) Phenylhydrazine
C) Phenylisothiocyanate D) Cyanogen bromide

--- Content provided by⁠ FirstRanker.com ---

12. Recombinant Human Insulin differ from bovine Insulin by
A) Biological activity B) Aminoacid sequence
C) Position of disulfide bonds D) Side chains
13. A 45 year old software engineer vegetarian by diet goes for master health checkup,
report shows elevated homocysteine levels. Hyperhomocysteinemia can occur in all

--- Content provided by‌ FirstRanker.com ---

the following Vitamin deficiency EXCEPT
A) Pyridoxine B) Cyanocobalamin C) Pantothenic acid D) Folic acid
14. All are true about Lysine EXCEPT
A) An essential aminoacid B) Ketogenic
C) Deficient in Cereals D) Deficient in Pulses

--- Content provided by‍ FirstRanker.com ---

15. All of the following metabolic disorders are associated with mental retardation EXCEPT
A) Phenylketonuria B) Von Gierke's Disease
C) Maple syrup urine disease D) Morteaux Lamy Syndrome
16. An adult male in 4th decade presented with severe low back ache. Oochronosis is seen in
A) Tyrosinemia B) Carcinoid syndrome C) Albinism D) Alkaptonuria

--- Content provided by​ FirstRanker.com ---

17. Gastric acid secretion is stimulated by all EXCEPT
A) Gastrin B) Pepsin C) Vagal stimulation D) Histamine
18. Proteinuria is not a feature in
A) Diabetes insipidus B) Multiple myeloma
C) Acute Glomerulonephritis D) Nephrotic syndrome

--- Content provided by‌ FirstRanker.com ---

19. Renal stones may contain any of the following constituents EXCEPT
A) Uric acid B) Calcium C) Cholesterol D) Cystine
20. A 50 year old male presented with Chronic Renal Failure and investigated for the
same. Which ion in serum is decreased in Chronic Renal Failure?
A) Potassium B) Phosphate C) Hydrogen D) Bicarbonate

--- Content provided by‍ FirstRanker.com ---

*********
[MBBS 0825]