D
r. . MEDICAL
[MBBS 0725] JULY 2025 Sub. Code :6061
M.B.B.S. DEGREE EXAMINATION
SECOND PROFESSIONAL ? (CBME)
PAPER I ? PHARMACOLOGY
Q.P. Code: 526061
Time: 20 Minutes
Maximum : 20 Marks
Answer All Questions
Shade the correct answer with Black or Blue ink ball point pen
SET - C
III. Multiple Choice Questions:
(20 x 1 = 20)
1. Select the ergot compound which is primarily used for dementia:
2. Sulfasalazine is used in the following disease(s):
A) Bacillary dysentery B) Ulcerative colitis
C) Rheumatoid arthritis D) Both `B' and `C' are correct
3. Reflex bronchoconstriction is most likely to occur with the following form of
A) Metered dose spray of drug in solution B) Dry powder rota cap
C) Nebuliser D) Nebuliser with spacer
4. Select the anaesthetic that increases the blood pressure:
A) Halothane B) Fentanyl C) Ketamine D) Diazepam
A) Gabapentin B) Vigabatrin C) Lamotrigine D) Clobazam
6. The major limitation in the use of clozapine for treatment of schizophrenia is:
A) Its potential to cause agranulocytosis
B) Its inability to benefit negative symptoms of schizophrenia
D) Production of hyperprolactinemia
7. Choose the correct statement about the use of propranolol in anxiety:
A) Being non-sedative, it is the drug of choice in chronic anxiety states
B) It suppresses the psychological component of anxiety
D) Both `B' and `C' are correct
8. Strychnine produces convulsions by:
A) Stimulating NMDA receptors
B) Facilitating the excitatory transmitter glutamate
D) Blocking the inhibitory transmitter glycine
9. Beneficial effect / effects of diuretics in CHF patients include the following:
A) Symptomatic relief B) Regression of pathological changes
C) Prolongation of life expectancy D) Both `A' and `C'
... 2 ...
10. Organic nitrates have predominantly venodilator action because:
A) They are selectively concentrated in veins
B) Veins express larger quantities of enzymes that generate nitric oxide from nitrates
D) All of the above are correct
11. Coronary steal phenomenon has been noted most frequently with:
A) Glyceryl trinitrate B) Dipyridamole C) Propranolol D) Diltiazem
12. Recombinant human erythropoietin is indicated for:
C) Patients of thalassemia D) Anaemia in chronic renal failure patients
13. Which of the following hypolipidemic drugs is most effective in raising HDL-
cholesterol level?
A) Nicotinic acid B) Fenofibrate C) Cholestyramine D) Pravastatin
A) Increases volume of distribution of the drug
B) Facilitates glomerular filtration of the drug
C) Minimises drug interactions
D) Decreases volume of distribution of the drug
A) Tolerance B) Physical dependence
C) Psychological dependence D) Placebo effect
16. The plasma half-life of penicillin-G is longer in the new born because their:
A) Plasma protein level is low
C) Glomerular filtration rate is low
D) Tubular transport mechanisms are not well developed
17. Receptors perform the following function/functions:
A) Ligand recognition
C) Both ligand recognition and signal transduction
D) Disposal of agonists and antagonists
18. Which of the following is a relatively cerebro selective anticholinesterase found to
afford symptomatic improvement in Alzheimer's disease:
19. Hyoscine differs from atropine in that it:
A) Exerts depressant effects on the CNS at relatively low doses
B) Exerts more potent effects on the heart than on the eye
C) Is longer acting
20. Choose the drug which is used as a short-term inotropic in severe congestive heart
failure and has selective adrenergic 1 agonistic activity but no dopaminergic
agonistic activity:
A) Dopamine B) Dobutamine C) Amrinone D) Salmeterol
[MBBS 0725]
r. . MEDICAL
[MBBS 0725] JULY 2025 Sub. Code :6061
M.B.B.S. DEGREE EXAMINATION
--- Content provided by FirstRanker.com ---
(For the candidates admitted from the Academic Year 2019 - 2020)SECOND PROFESSIONAL ? (CBME)
PAPER I ? PHARMACOLOGY
--- Content provided by FirstRanker.com ---
Q.P. Code: 526061
Time: 20 Minutes
--- Content provided by FirstRanker.com ---
Maximum : 20 Marks
Answer All Questions
Shade the correct answer with Black or Blue ink ball point pen
SET - C
--- Content provided by FirstRanker.com ---
III. Multiple Choice Questions:
(20 x 1 = 20)
1. Select the ergot compound which is primarily used for dementia:
--- Content provided by FirstRanker.com ---
A) Bromocriptine B) Ergotamine C) Codergocrine D) Methysergide2. Sulfasalazine is used in the following disease(s):
A) Bacillary dysentery B) Ulcerative colitis
C) Rheumatoid arthritis D) Both `B' and `C' are correct
3. Reflex bronchoconstriction is most likely to occur with the following form of
--- Content provided by FirstRanker.com ---
inhaled anti-asthma medication:A) Metered dose spray of drug in solution B) Dry powder rota cap
C) Nebuliser D) Nebuliser with spacer
4. Select the anaesthetic that increases the blood pressure:
A) Halothane B) Fentanyl C) Ketamine D) Diazepam
--- Content provided by FirstRanker.com ---
5. Select the anti-convulsant drug that acts as a GABA transaminase inhibitor:A) Gabapentin B) Vigabatrin C) Lamotrigine D) Clobazam
6. The major limitation in the use of clozapine for treatment of schizophrenia is:
A) Its potential to cause agranulocytosis
B) Its inability to benefit negative symptoms of schizophrenia
--- Content provided by FirstRanker.com ---
C) High incidence of extrapyramidal side effectsD) Production of hyperprolactinemia
7. Choose the correct statement about the use of propranolol in anxiety:
A) Being non-sedative, it is the drug of choice in chronic anxiety states
B) It suppresses the psychological component of anxiety
--- Content provided by FirstRanker.com ---
C) It suppresses the autonomic manifestations of acutely stressful situationsD) Both `B' and `C' are correct
8. Strychnine produces convulsions by:
A) Stimulating NMDA receptors
B) Facilitating the excitatory transmitter glutamate
--- Content provided by FirstRanker.com ---
C) Blocking the inhibitory transmitter GABAD) Blocking the inhibitory transmitter glycine
9. Beneficial effect / effects of diuretics in CHF patients include the following:
A) Symptomatic relief B) Regression of pathological changes
C) Prolongation of life expectancy D) Both `A' and `C'
--- Content provided by FirstRanker.com ---
... 2 ...... 2 ...
10. Organic nitrates have predominantly venodilator action because:
A) They are selectively concentrated in veins
B) Veins express larger quantities of enzymes that generate nitric oxide from nitrates
--- Content provided by FirstRanker.com ---
C) Venous smooth muscle has greater capacity to relaxD) All of the above are correct
11. Coronary steal phenomenon has been noted most frequently with:
A) Glyceryl trinitrate B) Dipyridamole C) Propranolol D) Diltiazem
12. Recombinant human erythropoietin is indicated for:
--- Content provided by FirstRanker.com ---
A) Megaloblastic anaemia B) Haemolytic anaemiaC) Patients of thalassemia D) Anaemia in chronic renal failure patients
13. Which of the following hypolipidemic drugs is most effective in raising HDL-
cholesterol level?
A) Nicotinic acid B) Fenofibrate C) Cholestyramine D) Pravastatin
--- Content provided by FirstRanker.com ---
14. High plasma protein binding:A) Increases volume of distribution of the drug
B) Facilitates glomerular filtration of the drug
C) Minimises drug interactions
D) Decreases volume of distribution of the drug
--- Content provided by FirstRanker.com ---
15. Microsomal enzyme induction can be a cause of:A) Tolerance B) Physical dependence
C) Psychological dependence D) Placebo effect
16. The plasma half-life of penicillin-G is longer in the new born because their:
A) Plasma protein level is low
--- Content provided by FirstRanker.com ---
B) Drug metabolizing enzymes are immatureC) Glomerular filtration rate is low
D) Tubular transport mechanisms are not well developed
17. Receptors perform the following function/functions:
A) Ligand recognition
--- Content provided by FirstRanker.com ---
B) Signal transductionC) Both ligand recognition and signal transduction
D) Disposal of agonists and antagonists
18. Which of the following is a relatively cerebro selective anticholinesterase found to
afford symptomatic improvement in Alzheimer's disease:
--- Content provided by FirstRanker.com ---
A) Donepezil B) Gemfibrozil C) Pyridostigmine D) Pyritinol19. Hyoscine differs from atropine in that it:
A) Exerts depressant effects on the CNS at relatively low doses
B) Exerts more potent effects on the heart than on the eye
C) Is longer acting
--- Content provided by FirstRanker.com ---
D) Has weaker anti motion sickness activity20. Choose the drug which is used as a short-term inotropic in severe congestive heart
failure and has selective adrenergic 1 agonistic activity but no dopaminergic
agonistic activity:
A) Dopamine B) Dobutamine C) Amrinone D) Salmeterol
--- Content provided by FirstRanker.com ---
**********[MBBS 0725]