D
r. . MEDICAL
[MBBS 0725] JULY 2025 Sub. Code :6061
M.B.B.S. DEGREE EXAMINATION
SECOND PROFESSIONAL ? (CBME)
PAPER I ? PHARMACOLOGY
Q.P. Code: 526061
Time: 20 Minutes
Maximum : 20 Marks
Answer All Questions
Shade the correct answer with Black or Blue ink ball point pen
SET - A
III. Multiple Choice Questions:
(20 x 1 = 20)
1. High plasma protein binding:
B) Facilitates glomerular filtration of the drug
C) Minimises drug interactions
D) Decreases volume of distribution of the drug
2. Microsomal enzyme induction can be a cause of:
C) Psychological dependence D) Placebo effect
3. The plasma half-life of penicillin-G is longer in the new born because their:
A) Plasma protein level is low
B) Drug metabolizing enzymes are immature
D) Tubular transport mechanisms are not well developed
4. Receptors perform the following function/functions:
A) Ligand recognition
B) Signal transduction
D) Disposal of agonists and antagonists
5. Which of the following is a relatively cerebro selective anticholinesterase found to
afford symptomatic improvement in Alzheimer's disease:
A) Donepezil B) Gemfibrozil C) Pyridostigmine D) Pyritinol
A) Exerts depressant effects on the CNS at relatively low doses
B) Exerts more potent effects on the heart than on the eye
C) Is longer acting
D) Has weaker anti motion sickness activity
failure and has selective adrenergic 1 agonistic activity but no dopaminergic
agonistic activity:
A) Dopamine B) Dobutamine C) Amrinone D) Salmeterol
8. Select the ergot compound which is primarily used for dementia:
... 2 ...
... 2 ...
9. Sulfasalazine is used in the following disease(s):
A) Bacillary dysentery B) Ulcerative colitis
10. Reflex bronchoconstriction is most likely to occur with the following form of
inhaled anti-asthma medication:
A) Metered dose spray of drug in solution B) Dry powder rota cap
C) Nebuliser D) Nebuliser with spacer
A) Halothane B) Fentanyl C) Ketamine D) Diazepam
12. Select the anti-convulsant drug that acts as a GABA transaminase inhibitor:
A) Gabapentin B) Vigabatrin C) Lamotrigine D) Clobazam
13. The major limitation in the use of clozapine for treatment of schizophrenia is:
B) Its inability to benefit negative symptoms of schizophrenia
C) High incidence of extrapyramidal side effects
D) Production of hyperprolactinemia
14. Choose the correct statement about the use of propranolol in anxiety:
B) It suppresses the psychological component of anxiety
C) It suppresses the autonomic manifestations of acutely stressful situations
D) Both `B' and `C' are correct
15. Strychnine produces convulsions by:
B) Facilitating the excitatory transmitter glutamate
C) Blocking the inhibitory transmitter GABA
D) Blocking the inhibitory transmitter glycine
16. Beneficial effect / effects of diuretics in CHF patients include the following:
C) Prolongation of life expectancy D) Both `A' and `C'
17. Organic nitrates have predominantly venodilator action because:
A) They are selectively concentrated in veins
B) Veins express larger quantities of enzymes that generate nitric oxide from nitrates
D) All of the above are correct
18. Coronary steal phenomenon has been noted most frequently with:
A) Glyceryl trinitrate B) Dipyridamole C) Propranolol D) Diltiazem
19. Recombinant human erythropoietin is indicated for:
C) Patients of thalassemia D) Anaemia in chronic renal failure patients
20. Which of the following hypolipidemic drugs is most effective in raising HDL-
cholesterol level?
A) Nicotinic acid B) Fenofibrate C) Cholestyramine D) Pravastatin
[MBBS 0725]
r. . MEDICAL
[MBBS 0725] JULY 2025 Sub. Code :6061
M.B.B.S. DEGREE EXAMINATION
--- Content provided by FirstRanker.com ---
(For the candidates admitted from the Academic Year 2019 - 2020)SECOND PROFESSIONAL ? (CBME)
PAPER I ? PHARMACOLOGY
--- Content provided by FirstRanker.com ---
Q.P. Code: 526061
Time: 20 Minutes
--- Content provided by FirstRanker.com ---
Maximum : 20 Marks
Answer All Questions
Shade the correct answer with Black or Blue ink ball point pen
SET - A
--- Content provided by FirstRanker.com ---
III. Multiple Choice Questions:
(20 x 1 = 20)
1. High plasma protein binding:
--- Content provided by FirstRanker.com ---
A) Increases volume of distribution of the drugB) Facilitates glomerular filtration of the drug
C) Minimises drug interactions
D) Decreases volume of distribution of the drug
2. Microsomal enzyme induction can be a cause of:
--- Content provided by FirstRanker.com ---
A) Tolerance B) Physical dependenceC) Psychological dependence D) Placebo effect
3. The plasma half-life of penicillin-G is longer in the new born because their:
A) Plasma protein level is low
B) Drug metabolizing enzymes are immature
--- Content provided by FirstRanker.com ---
C) Glomerular filtration rate is lowD) Tubular transport mechanisms are not well developed
4. Receptors perform the following function/functions:
A) Ligand recognition
B) Signal transduction
--- Content provided by FirstRanker.com ---
C) Both ligand recognition and signal transductionD) Disposal of agonists and antagonists
5. Which of the following is a relatively cerebro selective anticholinesterase found to
afford symptomatic improvement in Alzheimer's disease:
A) Donepezil B) Gemfibrozil C) Pyridostigmine D) Pyritinol
--- Content provided by FirstRanker.com ---
6. Hyoscine differs from atropine in that it:A) Exerts depressant effects on the CNS at relatively low doses
B) Exerts more potent effects on the heart than on the eye
C) Is longer acting
D) Has weaker anti motion sickness activity
--- Content provided by FirstRanker.com ---
7. Choose the drug which is used as a short-term inotropic in severe congestive heartfailure and has selective adrenergic 1 agonistic activity but no dopaminergic
agonistic activity:
A) Dopamine B) Dobutamine C) Amrinone D) Salmeterol
8. Select the ergot compound which is primarily used for dementia:
--- Content provided by FirstRanker.com ---
A) Bromocriptine B) Ergotamine C) Codergocrine D) Methysergide... 2 ...
... 2 ...
9. Sulfasalazine is used in the following disease(s):
A) Bacillary dysentery B) Ulcerative colitis
--- Content provided by FirstRanker.com ---
C) Rheumatoid arthritis D) Both `B' and `C' are correct10. Reflex bronchoconstriction is most likely to occur with the following form of
inhaled anti-asthma medication:
A) Metered dose spray of drug in solution B) Dry powder rota cap
C) Nebuliser D) Nebuliser with spacer
--- Content provided by FirstRanker.com ---
11. Select the anaesthetic that increases the blood pressure:A) Halothane B) Fentanyl C) Ketamine D) Diazepam
12. Select the anti-convulsant drug that acts as a GABA transaminase inhibitor:
A) Gabapentin B) Vigabatrin C) Lamotrigine D) Clobazam
13. The major limitation in the use of clozapine for treatment of schizophrenia is:
--- Content provided by FirstRanker.com ---
A) Its potential to cause agranulocytosisB) Its inability to benefit negative symptoms of schizophrenia
C) High incidence of extrapyramidal side effects
D) Production of hyperprolactinemia
14. Choose the correct statement about the use of propranolol in anxiety:
--- Content provided by FirstRanker.com ---
A) Being non-sedative, it is the drug of choice in chronic anxiety statesB) It suppresses the psychological component of anxiety
C) It suppresses the autonomic manifestations of acutely stressful situations
D) Both `B' and `C' are correct
15. Strychnine produces convulsions by:
--- Content provided by FirstRanker.com ---
A) Stimulating NMDA receptorsB) Facilitating the excitatory transmitter glutamate
C) Blocking the inhibitory transmitter GABA
D) Blocking the inhibitory transmitter glycine
16. Beneficial effect / effects of diuretics in CHF patients include the following:
--- Content provided by FirstRanker.com ---
A) Symptomatic relief B) Regression of pathological changesC) Prolongation of life expectancy D) Both `A' and `C'
17. Organic nitrates have predominantly venodilator action because:
A) They are selectively concentrated in veins
B) Veins express larger quantities of enzymes that generate nitric oxide from nitrates
--- Content provided by FirstRanker.com ---
C) Venous smooth muscle has greater capacity to relaxD) All of the above are correct
18. Coronary steal phenomenon has been noted most frequently with:
A) Glyceryl trinitrate B) Dipyridamole C) Propranolol D) Diltiazem
19. Recombinant human erythropoietin is indicated for:
--- Content provided by FirstRanker.com ---
A) Megaloblastic anaemia B) Haemolytic anaemiaC) Patients of thalassemia D) Anaemia in chronic renal failure patients
20. Which of the following hypolipidemic drugs is most effective in raising HDL-
cholesterol level?
A) Nicotinic acid B) Fenofibrate C) Cholestyramine D) Pravastatin
--- Content provided by FirstRanker.com ---
**********[MBBS 0725]