[MBBS 0325] MARCH 2025 Sub. Code :6061
M.B.B.S. DEGREE EXAMINATIONS
(For the candidates admitted from the Academic Year 2019 - 2020)
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SECOND PROFESSIONAL ? SUPPLEMENTARY - (CBME)
PAPER I ? PHARMACOLOGY
Q.P. Code: 526061
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Time: Three hours
Maximum: 100 Marks (80 Theory + 20MCQs)
Answer all the Questions
I. Essay:
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(2 x 15 = 30)
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(3+9+3)1. 55-year-old male presented with the complaints of tightness and discomfort
over middle part of chest, more so after exertion which gets relieved after
5-10 minutes of rest. His BP was 124/82mmHg, pulse 90/min. Stress test was
positive, a diagnosis of classical angina was made and he was started on drugs.
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a) Enumerate the drugs used in angina.b) Discuss the mechanism of action, uses and adverse effects of Nitrates.
c) Explain about Nitrate Tolerance and Dependence.
(1+2+3+7+2)
2. A 45-year-old farmer brought with complaints of altered sensorium,
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breathlessness, Profuse sweating. Attender gives history of spraying ofpesticides by him.
a) What is the diagnosis?
b) What other signs and symptoms you will look for?
c) Explain in detail the specific management in this case.
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d) Add a note on ageing of enzyme.II. Write Short notes on:
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(10 x 5 = 50)1. Explain the orders of kinetics with example.
2. Write the mechanism of action, uses and adverse effect of Amiodarone.
3. Give the rationale for combining Adrenaline with Lignocaine and write
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two contraindications for the use of adrenaline.4. Enumerate second generation Antihistamines. What are its advantages over
First generation and write two therapeutic uses?
5. Describe the mechanism of action, uses and adverse effects of Sodium
valproate.
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6. Pharmacotherapy of Status asthmaticus.7. Describe the therapeutic uses, adverse effects and contraindications of Morphine.
8. Describe the therapeutic uses of Loop diuretics and what are its drug indications?
9. List the parenteral iron preparations and write its indications.
10. Explain Autonomy and Maleficence in bioethics.
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