MEDICAL
[MBBS 0325] MARCH 2025 Sub. Code :6062
M.B.B.S. DEGREE EXAMINATIONS
(For the candidates admitted from the Academic Year 2019-2020)
PAPER II ? PHARMACOLOGY
Q.P. Code: 526062
Time: 20 Minutes
Answer All Questions
Shade the correct answer with Black of Blue ink ball point pen
SET - D
(20 x 1 = 20)
1. Metoclopramide has the following actions except:
C) Increases gastric peristalsis D) Increases intestinal peristalsis
2. Choose the correct statement about lactulose:
A) It stimulates myenteric neurons to enhance gut peristalsis
B) Administered orally it acts as a purgative within 2-4 hours
D) All of the above
3. A 3-year-old child was given one tablet three times a day to control loose motions. The
diarrhoea stopped but next day the child was brought in a toxic condition with abdominal
distention and vomiting. He had paralytic ileus, mild dehydration, low blood pressure and
A) Iodochlorhydroxyquinline B) Furazolidone C) Loperamide D) Metronidazole
4. Trimethoprim is combined with sulfamethoxazole in a ratio of 1:5 to yield a steady state
plasma concentration ratio of:
A) Trimethoprim 1: Sulfamethoxazole 5 B) Trimethoprim 5: Sulfamethoxazole 1
5. If a patient gives history of urticaria, itching and swelling of lips following injection of
penicillin G, then:
A) He will develop similar reaction whenever penicillin is injected
B) He can be given ampicillin safely
D) All natural and semisynthetic penicillins are contraindicated for him
6. Combination therapy with two (or more) antimicrobials is superior to monotherapy with any
single effective drug in case of the following diseases except:
A) Typhoid fever B) Leprosy C) HIV D) Tuberculosis
A) Isoniazid B) Rifampicin C) Pyrazinamide D) Ethambutol
... 2 ...
... 2 ...
8. The polyene antibiotics act by:
B) Binding to ergosterol and creating micropores
C) Inhibiting fungal DNA synthesis
D) Disorienting microtubules in fungal cells
9. Select the drug which directly inhibits HIV-reverse transcriptase without the need for
A) Nelfinavir B) Nevirapine C) Stavudine D) Didanosine
10. Patients treated with the following anticancer drug are likely to develop a disulfiram like
reaction on taking alcohol:
A) Dacarbazine B) Procarbazine C) Melphalan D) Hydroxyurea
A) Permethrin B) Sulfur C) Crotamiton D) Gentian Violet
12. BAL is used as a Chelating agent for the following heavy metals except
A) Arsenic Poisoning B) Mercury Poisoning
C) Cadmium Poisoning D) Nickel Poisoning
A) Growth hormone B) Insulin C) Thyrotropin D) All of the above
14. Overtreatment with the following thyroid inhibitor results in enlargement of the thyroid:
A) Lugol's iodine B) Radioactive iodine C) Carbimazole D) All of the above
15. The second-generation sulfonylurea hypoglycaemics differ from the first-generation ones in
A) Are more potent
B) Are longer acting
C) Do not lower blood sugar in nondiabetic subjects
D) Are less prone to cause hypoglycaemic reaction
A) Cortisone B) Hydrocortisone C) Triamcinolone D) Methyl prednisolone
17. Finasteride acts by:
A) Blocking testosterone receptors in the prostate gland
B) Reducing testosterone secretion from testes
D) Lowering circulating as well as prostatic dihydrotestosterone concentration
18. Select the tissue that is most sensitive to oxytocin:
A) Myometrium B) Myoepithelium of mammary alveoli
C) Vascular smooth muscle D) Renal collecting ducts
A) Paget's disease B) Senile osteoporosis C) Rickets D) Osteolytic bony metastasis
20. The following antiulcer drug does not act by reducing the secretion or neutralizing gastric acid:
A) Magaldrate B) Sucralfate C) Misoprostol D) Omeprazole
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[MBBS 0325] MARCH 2025 Sub. Code :6062
M.B.B.S. DEGREE EXAMINATIONS
(For the candidates admitted from the Academic Year 2019-2020)
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SECOND PROFESSIONAL ? SUPPLEMENTARY - (CBME)PAPER II ? PHARMACOLOGY
Q.P. Code: 526062
Time: 20 Minutes
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Maximum : 20 MarksAnswer All Questions
Shade the correct answer with Black of Blue ink ball point pen
SET - D
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III. Multiple Choice Questions:(20 x 1 = 20)
1. Metoclopramide has the following actions except:
--- Content provided by FirstRanker.com ---
A) Increases lower esophageal sphincter tone B) Increases tone of pyloric sphincterC) Increases gastric peristalsis D) Increases intestinal peristalsis
2. Choose the correct statement about lactulose:
A) It stimulates myenteric neurons to enhance gut peristalsis
B) Administered orally it acts as a purgative within 2-4 hours
--- Content provided by FirstRanker.com ---
C) It is an osmotic laxative that produces soft but formed stoolsD) All of the above
3. A 3-year-old child was given one tablet three times a day to control loose motions. The
diarrhoea stopped but next day the child was brought in a toxic condition with abdominal
distention and vomiting. He had paralytic ileus, mild dehydration, low blood pressure and
--- Content provided by FirstRanker.com ---
sluggish reflexes. Which antidiarrhoeal drug could have caused this condition:A) Iodochlorhydroxyquinline B) Furazolidone C) Loperamide D) Metronidazole
4. Trimethoprim is combined with sulfamethoxazole in a ratio of 1:5 to yield a steady state
plasma concentration ratio of:
A) Trimethoprim 1: Sulfamethoxazole 5 B) Trimethoprim 5: Sulfamethoxazole 1
--- Content provided by FirstRanker.com ---
C) Trimethoprim 1: Sulfamethoxazole 20 D) Trimethoprim 20: Sulfamethoxazole 15. If a patient gives history of urticaria, itching and swelling of lips following injection of
penicillin G, then:
A) He will develop similar reaction whenever penicillin is injected
B) He can be given ampicillin safely
--- Content provided by FirstRanker.com ---
C) He can be given oral phenoxymethyl penicillin safelyD) All natural and semisynthetic penicillins are contraindicated for him
6. Combination therapy with two (or more) antimicrobials is superior to monotherapy with any
single effective drug in case of the following diseases except:
A) Typhoid fever B) Leprosy C) HIV D) Tuberculosis
--- Content provided by FirstRanker.com ---
7. Which of the following antitubercular drugs is not hepatotoxic:A) Isoniazid B) Rifampicin C) Pyrazinamide D) Ethambutol
... 2 ...
... 2 ...
8. The polyene antibiotics act by:
--- Content provided by FirstRanker.com ---
A) Inhibiting fungal cytochrome P450 enzymeB) Binding to ergosterol and creating micropores
C) Inhibiting fungal DNA synthesis
D) Disorienting microtubules in fungal cells
9. Select the drug which directly inhibits HIV-reverse transcriptase without the need for
--- Content provided by FirstRanker.com ---
intracellular activation by phosphorylation:A) Nelfinavir B) Nevirapine C) Stavudine D) Didanosine
10. Patients treated with the following anticancer drug are likely to develop a disulfiram like
reaction on taking alcohol:
A) Dacarbazine B) Procarbazine C) Melphalan D) Hydroxyurea
--- Content provided by FirstRanker.com ---
11. Drugs used for Pediculosis are all exceptA) Permethrin B) Sulfur C) Crotamiton D) Gentian Violet
12. BAL is used as a Chelating agent for the following heavy metals except
A) Arsenic Poisoning B) Mercury Poisoning
C) Cadmium Poisoning D) Nickel Poisoning
--- Content provided by FirstRanker.com ---
13. Somatostatin inhibits the release of:A) Growth hormone B) Insulin C) Thyrotropin D) All of the above
14. Overtreatment with the following thyroid inhibitor results in enlargement of the thyroid:
A) Lugol's iodine B) Radioactive iodine C) Carbimazole D) All of the above
15. The second-generation sulfonylurea hypoglycaemics differ from the first-generation ones in
--- Content provided by FirstRanker.com ---
that they:A) Are more potent
B) Are longer acting
C) Do not lower blood sugar in nondiabetic subjects
D) Are less prone to cause hypoglycaemic reaction
--- Content provided by FirstRanker.com ---
16. Select the compound that is preferred for high dose intravenous corticosteroid pulse therapy:A) Cortisone B) Hydrocortisone C) Triamcinolone D) Methyl prednisolone
17. Finasteride acts by:
A) Blocking testosterone receptors in the prostate gland
B) Reducing testosterone secretion from testes
--- Content provided by FirstRanker.com ---
C) Reducing LH secretion from pituitaryD) Lowering circulating as well as prostatic dihydrotestosterone concentration
18. Select the tissue that is most sensitive to oxytocin:
A) Myometrium B) Myoepithelium of mammary alveoli
C) Vascular smooth muscle D) Renal collecting ducts
--- Content provided by FirstRanker.com ---
19. Bisphosphonates are beneficial in the following conditions except:A) Paget's disease B) Senile osteoporosis C) Rickets D) Osteolytic bony metastasis
20. The following antiulcer drug does not act by reducing the secretion or neutralizing gastric acid:
A) Magaldrate B) Sucralfate C) Misoprostol D) Omeprazole
********
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[MBBS 0325]