Date: 01-01-2018
0819E373
First Year MBBS Examination
I MBBS Biochemistry Paper 1
Time: 3 hours
Instructions:
1. Answer to the points.
2. Figure to the right indicates marks.
3. Use separate answer books for each
4. Draw diagrams wherever necessary.
5. Write legibly.
Section 1
1. Write short notes on the following (10)
b) Sickel cell disease
c) Atherosclerosis(A.228)(C. 317,326)
2. Write Short notes of (any three)
(9)
a) Isoenzymes(A.79)(C.112)
b) Significance of 2-3 BPG
c) Prostaglandins(A. 243)(C.644)
d) Glycogen(A. 144)(C.269)
e) Allosteric enzymes(A. 66)(C.95)
(6)
a) ELISA(A. 437)(C.729)
b) Respiratory acidosis (A.405) (C.482)
c) Liver function test (A.357) (C.453)
4. Write Short notes on (any two)
(10)
a) Blood glucose regulation (A.159)
(C.676)
bodies (A.205)(C.293)
c) Hexose monophosphate shunt (HMP)
and its significance (A.144) (C.270)
5. Write Short notes on (any two)
a) Detoxification - Phase II reaction
b) Uses of radioactive isotopes (A.682
(C.717)
c) Tumor marker(A. 666)(C.691)
e) Uncoupler
6. Case report: A middle aged stress
prone executive was admitted to ICCU
under the complain of severe chest pain
history of young
(6)
death due to cardiac failure. This patient was
diagnosed for MI and hypercholesterolemia.
175 mg/dl and HDL-cholestrol was 30
mg/dl. To reduce cholesterol he was given
lovastatin.
a) Write normal values of lipid profile.
c) Why high levels of LDL-C is not good
sign?
d) Why high levels of HDL- C are
considered good?
synthesis in the body and how?
f) What is the mode of action of
Lovastatin?
0819E373
First Year MBBS Examination
I MBBS Biochemistry Paper 1
Time: 3 hours
--- Content provided by FirstRanker.com ---
Max Marks: 50Instructions:
1. Answer to the points.
2. Figure to the right indicates marks.
3. Use separate answer books for each
--- Content provided by FirstRanker.com ---
section.4. Draw diagrams wherever necessary.
5. Write legibly.
Section 1
1. Write short notes on the following (10)
--- Content provided by FirstRanker.com ---
a) Galactosemia(A. 183)(C.277)b) Sickel cell disease
c) Atherosclerosis(A.228)(C. 317,326)
2. Write Short notes of (any three)
(9)
--- Content provided by FirstRanker.com ---
a) Isoenzymes(A.79)(C.112)
b) Significance of 2-3 BPG
c) Prostaglandins(A. 243)(C.644)
d) Glycogen(A. 144)(C.269)
e) Allosteric enzymes(A. 66)(C.95)
--- Content provided by FirstRanker.com ---
3. Discuss Any TWO(6)
a) ELISA(A. 437)(C.729)
b) Respiratory acidosis (A.405) (C.482)
c) Liver function test (A.357) (C.453)
--- Content provided by FirstRanker.com ---
Section 24. Write Short notes on (any two)
(10)
a) Blood glucose regulation (A.159)
(C.676)
--- Content provided by FirstRanker.com ---
b) Formation and breakdown of ketonebodies (A.205)(C.293)
c) Hexose monophosphate shunt (HMP)
and its significance (A.144) (C.270)
5. Write Short notes on (any two)
--- Content provided by FirstRanker.com ---
(9)a) Detoxification - Phase II reaction
b) Uses of radioactive isotopes (A.682
(C.717)
c) Tumor marker(A. 666)(C.691)
--- Content provided by FirstRanker.com ---
d) Immunoglobulin (A.649) (C.186)e) Uncoupler
6. Case report: A middle aged stress
prone executive was admitted to ICCU
under the complain of severe chest pain
--- Content provided by FirstRanker.com ---
and discomfort. He also had familyhistory of young
(6)
death due to cardiac failure. This patient was
diagnosed for MI and hypercholesterolemia.
--- Content provided by FirstRanker.com ---
his total cholesterol was 450 mg/dl, TG was175 mg/dl and HDL-cholestrol was 30
mg/dl. To reduce cholesterol he was given
lovastatin.
a) Write normal values of lipid profile.
--- Content provided by FirstRanker.com ---
b) Calculate his LDL cholestrolc) Why high levels of LDL-C is not good
sign?
d) Why high levels of HDL- C are
considered good?
--- Content provided by FirstRanker.com ---
e) Which enzymes regulate choelstrolsynthesis in the body and how?
f) What is the mode of action of
Lovastatin?
--- Content provided by FirstRanker.com ---