Date: 09-01-2019
0819E373
First Year MBBS Examination
I MBBS Biochemistry Paper 1
Time: 3 hours
1. Answer to the points.
2. Figure to the right indicates marks.
3. Use separate answer books for
each section.
necessary.
5. Write legibly.
Section 1
1. Write short notes on the following
(10)
b) Von Gierk's disease
c) Biochemical basis of ammonia
toxicity
a) Physiologically important
(9)
glycosides
b) Serum enzymes in myocardial
c) Regulation of cholesterol synthesis
d) Acute intermittent porphyria
e) Suicidal inhibition of enzymes
3. Discuss Any TWO
(6)
linked immunosorbent assay)
b) Role of kidneys in regulation of
blood pH
c) Fluid mosaic model of cell
membrane
Section 2
4. Write Short notes on (any two)
a) Reciprocal regulation of
glycogenesis of glycogenolysis
b) Fatty acid synthase complex
c) Significance of HMP (hexoe mono
phosphate) shunt
a) Water pollutants
(9)
b) Oncogenes
c) Uncouplers of oxidative
d) Structure of immunoglobulin
e) Biological effects of radiation on
tissues
6. Case report:
(6)
who took only water for next 15 days
when his condition deteriorated, he was
admitted in a hospital blood level of
be decreased urine had ketone bodies,
urinary non protein nitrogen was
increased. Answer the following
questions (any six).
total circulating glucose daily. How
does brain obtain energy during
starvation?
2) Can brain utilize ketone bodies to
3) How does starvation trigger
gluconeogenesis and lipolysis?
4) What is the fate of amino nitrogen
generated in the liver during process
5) What are the sources of two
carbon atoms in urea molecule?
6) Why does ketoacidosis develop in
the patient?
amino acids" in the initial phase of
starvation?
8) What happens to alanine in the
initial phase of starvation?
0819E373
First Year MBBS Examination
I MBBS Biochemistry Paper 1
Time: 3 hours
--- Content provided by FirstRanker.com ---
Max Marks: 501. Answer to the points.
2. Figure to the right indicates marks.
3. Use separate answer books for
each section.
--- Content provided by FirstRanker.com ---
4. Draw diagrams wherevernecessary.
5. Write legibly.
Section 1
1. Write short notes on the following
--- Content provided by FirstRanker.com ---
a) Diabetic ketoacidosis(10)
b) Von Gierk's disease
c) Biochemical basis of ammonia
toxicity
--- Content provided by FirstRanker.com ---
2. Write Short notes of (any three)a) Physiologically important
(9)
glycosides
b) Serum enzymes in myocardial
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infarctionc) Regulation of cholesterol synthesis
d) Acute intermittent porphyria
e) Suicidal inhibition of enzymes
3. Discuss Any TWO
--- Content provided by FirstRanker.com ---
a) Application of ELISA (enzyme(6)
linked immunosorbent assay)
b) Role of kidneys in regulation of
blood pH
--- Content provided by FirstRanker.com ---
c) Fluid mosaic model of cell
membrane
Section 2
4. Write Short notes on (any two)
a) Reciprocal regulation of
--- Content provided by FirstRanker.com ---
(10)glycogenesis of glycogenolysis
b) Fatty acid synthase complex
c) Significance of HMP (hexoe mono
phosphate) shunt
--- Content provided by FirstRanker.com ---
5. Write Short notes on (any two)a) Water pollutants
(9)
b) Oncogenes
c) Uncouplers of oxidative
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phosphorylationd) Structure of immunoglobulin
e) Biological effects of radiation on
tissues
6. Case report:
--- Content provided by FirstRanker.com ---
During a hunger strike, one tudent(6)
who took only water for next 15 days
when his condition deteriorated, he was
admitted in a hospital blood level of
--- Content provided by FirstRanker.com ---
sugar and amino acids were found tobe decreased urine had ketone bodies,
urinary non protein nitrogen was
increased. Answer the following
questions (any six).
--- Content provided by FirstRanker.com ---
1) The brain consumes 65 % of thetotal circulating glucose daily. How
does brain obtain energy during
starvation?
2) Can brain utilize ketone bodies to
--- Content provided by FirstRanker.com ---
meet part of its energy requirement?3) How does starvation trigger
gluconeogenesis and lipolysis?
4) What is the fate of amino nitrogen
generated in the liver during process
--- Content provided by FirstRanker.com ---
of gluconeogenesis?5) What are the sources of two
carbon atoms in urea molecule?
6) Why does ketoacidosis develop in
the patient?
--- Content provided by FirstRanker.com ---
7) What happens to "branched chainamino acids" in the initial phase of
starvation?
8) What happens to alanine in the
initial phase of starvation?
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